Potential therapeutic applications of MDA-9/Syntenin-NF- κB-RKIP loop in human liver carcinoma.

CONCLUSION: Our data confirm the key role of MDA-9/Syntenin in HCC biology. The presence of a regulation loop among MDA-9/Syntenin, NF-κB and RKIP provide new pharmacological approaches.
PMID: 30608040 [PubMed - as supplied by publisher]

Source: Current Molecular Medicine - January 3, 2019 Category: Molecular Biology Authors: Notarbartolo M, Labbozzetta M, Pojero F, D'Alessandro N, Poma P Tags: Curr Mol Med Source Type: research