Short-term effect of low-, moderate-, and high-intensity exercise training on cerebral dopamine neurotrophic factor (CDNF) and oxidative stress biomarkers in brain male Wistar rats

AbstractNeurotrophic factors and exercise training are effective in the growth and survival of neuronal cells. These factors play a protective role against oxidative stress damage and have the same function as antioxidants. The purpose of this study was to investigate the effect of a session of endurance training with three different intensities on CDNF, SOD, and MDA levels of cerebral cortex in male rats. Thirty-two male Wistar rats (aged 20  weeks) were divided randomly into two control and training groups. The training group consisted of low-, moderate-, and high-intensity trainings. The training groups, after getting familiarization with the rodent treadmill, were dealt with an acute training session with three different intensities . The CDNF level of cerebral cortex was measured by ELISA assay, and the SOD and MDA levels of cerebral cortex by spectrophotometery. A significant difference was seen in the CDNF level between low- and high-intensity groups, as well as between high-intensity groups and control group (P = 0.001). The levels of SOD were increased significantly among all groups (except for control and low-intensity groups). The acute training with different intensities significantly prevents the increase in MDA level of cerebral cortex (P = 0.005). The result of this study shows that the physical exercise even in the short term can affect the protective factors and antioxidant system in neuronal cells. However, the benefits of hi...
Source: Comparative Clinical Pathology - Category: Pathology Source Type: research

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Houston-based Christus Foundation for Healthcare received a $3 million donation to finish construction on its East End clinic. Christus Foundation for Healthcare received the gift from Irving, Texas-based Catholic nonprofit health system Christus Health, according to a Nov. 11 press release. The funds will go toward completing construction on the new Christus St. Mary's Clinic building on the St. Austin Center campus at 2 002 S. Wayside Drive. The clinic is nearly doubling in size — from 4,500…
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Authors: Nagy P, Molnar B, Nemes B, Schupbach P, Windisch P Abstract The aim of this case series was the histologic evaluation of guided tissue regeneration utilizing deproteinized bovine bone mineral (DBBM) when regenerative surgery was combined with (test) or without (control) early orthodontic tooth movement. Core biopsy samples were harvested from previously defected sites after 9 months. The histologic section showed integration of DBBM particles in newly formed bone in the apical and middle thirds of the defect, while in the coronal part, graft materials were mainly embedded in connective tissues in the contr...
Source: International Journal of Periodontics and Restorative Dentistry - Category: Dentistry Tags: Int J Periodontics Restorative Dent Source Type: research
Authors: Al Balbeesi HO, Al Kawari HM, Al Tamimi AS, Al Mubarak I, Al Ibrahim KI, Divakar DD Abstract In the present study, the authors evaluated the association of canine impaction with different skeletal discrepancies in two planes of space (sagittal and vertical). Cephalometric and orthopantomographic radiographic images of 45 patients with one or more impacted canines were used in this retrospective study. Five radiographic morphologic parameters-ANB angle, canine angulation, angle between the Frankfort horizontal plane and the mandibular plane (FH-MP), Wits appraisal analysis, and axial inclination of the maxi...
Source: International Journal of Periodontics and Restorative Dentistry - Category: Dentistry Tags: Int J Periodontics Restorative Dent Source Type: research
[Cameroon Tribune] A genomic company known as 54gene is building the first pan-African Biobank that will target many diseases.
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Soft Matter, 2019, Accepted Manuscript DOI: 10.1039/C9SM02049G, PaperBing Jiang , Huichuang Guo, Li Zhao, Baocai Xu, Ce Wang, Changyao Liu, Haiming Fan The current research involves fabrication of a redox-responsive self-assembly system based on a ferrocene (Fc)-containing β-cyclodextrin (β-CD) derivative (βCD-EG-Fc). βCD-EG-Fc was synthesized, and its redox-sensitive self-assembly behavior was investigated using... The content of this RSS Feed (c) The Royal Society of Chemistry
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Soft Matter, 2019, Accepted Manuscript DOI: 10.1039/C9SM02004G, PaperYong-Zhen Chang, Yong Chen, Yu Liu Supramolecular hydrogels have received great attention because of their various fascinating applications. Herein, alkyl chains modified oligo(p-phenylenevinylene) (Py-OPV) derivative was synthesized. When assembled with cucurbit[7]uril, only its fluorescence intensity was... The content of this RSS Feed (c) The Royal Society of Chemistry
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Soft Matter, 2019, Accepted Manuscript DOI: 10.1039/C9SM01735F, PaperTapomoy Bhattacharjee, Sujit Sankar Datta Understanding how bacteria move in porous media is critical to applications in healthcare, agriculture, environmental remediation, and chemical sensing. Recent work has demonstrated that E. coli, which moves by run-and-tumble... The content of this RSS Feed (c) The Royal Society of Chemistry
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Photochem. Photobiol. Sci., 2019, Accepted Manuscript DOI: 10.1039/C9PP00410F, PaperMinoru Yamaji, Kazuhiro Tomonari, Keisuke Ikuma, Kenta Goto, Fumito Tani, Hideki Okamoto We prepared amide-heterocycle (HC) compounds having various aromatic -electron systems (Ar), such as phenyl, naphthyl, furyl, thienyl and phenanthryl moieties, and converted them as ligands to difluoroboronated complexes, Ar@HC. Blue... The content of this RSS Feed (c) The Royal Society of Chemistry
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This article is licensed under aCreative Commons Attribution-NonCommercial 3.0 Unported Licence.Cynthia Richard, Armaghan Fakhfouri, Melanie Colditz, Friedrich Striggow, Romy Kronstein-Wiedemann, Torsten Tonn, Mariana Medina-S ánchez, Oliver G. Schmidt, Thomas Gemming, Andreas Winkler SAW-based acoustofluidic blood platelet separation at 2.7 × 104 cells per s throughput in a comprehensively analysed and numerical simulated, wafer-scale manufactured device. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
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New J. Chem., 2019, Accepted Manuscript DOI: 10.1039/C9NJ04598H, LetterXiao Li, Xiao-Li Hu, Xinlong Wang, Qing-Qing Pan, Lei Liu, Zhong-Min Su The production of hydrogen via electrochemical water splitting combind with fuel cells is a promising way to realize sustainable energy system. Herein, we report a simple one-step, scalable glucose-blowing method... The content of this RSS Feed (c) The Royal Society of Chemistry
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