Brain-derived neurotrophic factor is a biomarker for subjective insomnia but not objectively assessable poor sleep continuity

ConclusionsIndependently of symptoms of depression or anxiety, sBDNF appears to be a biomarker for the clinical diagnosis of insomnia, but not for objectively assessed poor sleep continuity. A possible link between sBDNF and insomnia seems to be via regulation of REM-sleep, but not salivary morning cortisol.
Source: Journal of Psychiatric Research - Category: Psychiatry Source Type: research