Relationship of Ganciclovir Therapeutic Drug Monitoring with Clinical Efficacy and Patient Safety.
Conclusions: We did not observe any associations between ganciclovir TDM and clinical efficacy or safety endpoints. Routine ganciclovir TDM may be of limited value. Future studies may be warranted to identify specific populations with unpredictable pharmacokinetic and pharmacodynamics profiles in whom ganciclovir TDM may be of benefit.
PMID: 30602515 [PubMed - as supplied by publisher]
Source: Antimicrobial Agents and Chemotherapy - Category: Microbiology Authors: Ritchie BM, Barreto JN, Frazee E, Crow SA, Dierkhising RA, Jannetto PJ, Tosh PK, Razonable RR Tags: Antimicrob Agents Chemother Source Type: research