Transthoracic echocardiography guided percutaneous laser ablation of the interventricular septum: A successful sheep model for septal thickness reduction and one year follow-up

Hypertrophic cardiomyopathy (HCM) is a common genetic cardiovascular disease, causing breathlessness, chest pain, syncope and sudden death. One-year outcome of echo-guided transthoracic percutaneous laser ablation (TPLA) of the sheep interventricular septum was studied as a novel treatment to reduce the septal thickness. It may partially address the limitations of surgical myectomy and alcohol septal ablation in terms of trauma, safety, and efficacy.

Source: International Journal of Cardiology - January 4, 2019 Category: Cardiology Authors: Jianli Fu, Chao Sun, Fang Liu, Rui Hu, David H. Hsi, Shengjun Tuo, Hong Shao, Hong Yin, Jianmin Zheng, Jianlei Zhang, Jian Yang, Jun Zhang, Xiangping Guan, Liwen Liu Source Type: research