As You Age, Alcohol May Be Harder to Handle

FRIDAY, Jan. 4, 2019 -- Seniors may be more vulnerable to alcoholism, a psychologist warns. " As we age, it takes longer for the body to break down alcohol. It stays in the system longer. Tolerance also decreases. Excessive drinking can compromise...
Source: - Daily MedNews - Category: General Medicine Source Type: news

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Conclusions: The results indicate that self-efficacy and motivation are interrelated in improving long-term abstinence and PDA following residential treatments and may play a substantial role in recovery from AUD.Eur Addict Res
Source: European Addiction Research - Category: Addiction Source Type: research
This study deals with the synthesis and characterization of HAP biomaterials. It is prepared through wet chemical precipitation method at two different ranges of temperatures, 25°C-35 °C and 35°C-45 °C and is denoted as HAP1 and HAP2 respectively. Porous HAP provides a powerful bond to the bones, which interconnect mechanically foremost to a hard fixation of the bone and teeth. Porous HAP processed from polymeric sponge process had 60–70% porosity with interconnected porous of diameter 100–400 μm range using poly vinyl alcohol (PVA). HAP is phase pure at temperature 1150 °C and ge...
Source: Materials Science in Semiconductor Processing - Category: Materials Science Source Type: research
In this study, the LDH containing a kind of green inhibitor (sodium molybdate) was synthesized and utilized in a poly-vinyl alcohol (PVA) base coating applied on the aluminum (5054 series) surface. After evaluating the LDH performance, the inhibitor release from the LDH crystals was examined by changing significant parameters like MII/MIII (the molar ratio of divalent ions into trivalent ions), pH, aging time and temperature. In order to find the kinetic release of intercalated inhibitor a prediction model was introduced in 3.5% NaCl solution. The model expressed that the pH as the processing parameter has special effect o...
Source: Journal of Materials Research and Technology - Category: Materials Science Source Type: research
Authors: Liu Y, Huang X, Liu Y, Li D, Zhang J, Yang L Abstract Application value of hypersensitive C-reactive protein (hs-CRP), blood lactic acid (LAC) and myoglobin (Mb) in the combined detection of myocarditis was explored. A total of 107 patients with suspected myocarditis treated in The Second Nanning People's Hospital from January 2015 to December 2017 were retrospectively analyzed, of whom 81 patients diagnosed with myocarditis were enrolled into the research group, and 26 non-myocarditis individuals were enrolled into the control group. Fasting venous blood was drawn from all patients to detect the hs-CRP, L...
Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research
We present the first fatal case in the Netherlands and one of the few worldwide. Postmortem biological samples and the presumed abused unknown substance, sold as ant poison, were obtained. 3-MeO-PCP was detected, and the resulting concentration was 152 μg/l in whole blood. The presumed taken unknown sample was identified as 3-MeO-PCP and thus linked to the victim. The cause of death was a combination of 3-MeO-PCP, amphetamine, and alcohol. Improved diagnostic skills are necessary to face these emerging novel psychoactive substances also in light of public health and social risks.
Source: Journal of Forensic and Legal Medicine - Category: Forensic Medicine Source Type: research
CONCLUSIONS: No biochemical or significant histological liver toxicity for MTX was demonstrated when applying causality criteria for DILI. More studies with this methodology are necessary in order to improve the assessment of its frequency. PMID: 31105018 [PubMed - as supplied by publisher]
Source: Annals of Hepatology - Category: Gastroenterology Tags: Ann Hepatol Source Type: research
This study aimed to analyse the relationship between the JAK2-STAT3 signalling pathway and the ameliorating effect of HGF on NASH. MATERIAL AND METHODS: Mice were fed a high-fat diet (HFD) for 16 weeks, and then plasma and hepatic tissues were collected. Histological and clinical chemistry assays were performed to assess liver disease. The mRNA and protein levels of JAK2, STAT3, and c-Met were assessed by realtime PCR and western blotting, respectively. RESULTS: Serum ALT, AST, and TG levels were increased in NASH mice. Histological analysis showed different degrees of steatosis, inflammatory infiltrates, and fibro...
Source: Annals of Hepatology - Category: Gastroenterology Tags: Ann Hepatol Source Type: research
CONCLUSION: On the present study, the prevalence of heavy use of alcohol was high and associated with a poorer prognosis in hospitalized cirrhotic patients, increasing the risk of infection and death. PMID: 31103151 [PubMed - in process]
Source: Annals of Hepatology - Category: Gastroenterology Tags: Ann Hepatol Source Type: research
Authors: Fonseca F, Kulkarni B, Hastak M, Kumaran V, Varma V, Kapoor S Abstract INTRODUCTION AND AIM: 1. Study of liver explants - Etiologic types of end-stage chronic liver disease (ESCLD) and acute liver failure (ALF) in adults and children. 2. Assessment of donor steatosis and incidental granulomas. 3. Post-transplant liver biopsies. MATERIAL AND METHODS: Specimens of 180 explant hepatectomies, 173 donor wedge and 30 core liver biopsies, and 58 post transplant liver biopsies received in our department from April 2013 to March 2017. RESULTS: 1. Most common causes of ESCLD in adults were: alcohol related (...
Source: Annals of Hepatology - Category: Gastroenterology Tags: Ann Hepatol Source Type: research
CONCLUSIONS: In Mexican adults, deficient VD concentration and FL were not independently associated of caloric consumption and physical activity. PMID: 31103146 [PubMed - in process]
Source: Annals of Hepatology - Category: Gastroenterology Tags: Ann Hepatol Source Type: research
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