Epithelial-to-mesenchymal transition status of primary breast carcinomas and its correlation with metastatic behavior

ConclusionsThe EMT status of breast cancers, as defined by the presence of a core EMT gene expression signature is associated with non-basal-type tumors, but not with the pattern of distant metastasis. Of several potential immunohistochemical EMT markers, onlyNAT1 andTWIST1 expression levels were associated with the gene expression-based EMT status.

Source: Breast Cancer Research and Treatment - January 4, 2019 Category: Cancer & Oncology Source Type: research