Effect of Pretreatment Blood Pressure on Outcomes in Thrombolysed Acute Ischemic Stroke Patients: A Systematic Review and Meta-analysis

Blood pressure (BP) is an important determinant of functional outcome in acute ischemic stroke (AIS) patients treated with intravenous tissue plasminogen activator (IV-tPA). Current guidelines recommend a BP target of 185/110 mmHg before IV-tPA bolus and maintaining it at less than 180/105 mmHg for the first 24 hours. However, the effect of blood pressure on various outcome measures after systemic thrombolysis remains unclear.

Source: Journal of Stroke and Cerebrovascular Diseases - January 3, 2019 Category: Neurology Authors: Rebecca S.Y. Teng, Benjamin Y.Q. Tan, Samuel Miny, Nicholas L. Syn, Andrew F.W. Ho, Nicholas J.H. Ngiam, Leonard L.L. Yeo, Andrew M. Choong, Vijay K. Sharma Source Type: research