ElectroCore wins 5-year GammaCore federal supply deal

ElectroCore said yesterday it won a five-year Federal Supply Schedule Medical Equipment and Supply Contract with the U.S. Federal Government. Through the newly awarded contract, the Basking Ridge, N.J.-based company will supply its GammaCore non-invasive vagus nerve stimulation therapy to the Dept. of Veteran’s Affairs, the Dept. of Defense, the Bureau of Prisons, Indian Health Services and Public Health Services. The Basking Ridge, N.J.-based company’s GammaCore device is a non-invasive, hand-held vagus nerve stimulation device designed for the reduction of pain. The system is intended to be applied to the neck and applies a patented electrical stimulation through the skin to activate the vagus nerve. “ElectroCore continues to focus on making GammaCore affordable, accessible and broadly available. With the FSS contract, we will deepen our commitment to the underserved patient population diagnosed with migraine or cluster headache, and are one step closer to ensuring patients who may benefit from gammaCore have access to this safe and effective therapy,” CEO Frank Amato said in a press release. Last November, ElectroCore said that it won expanded FDA 510(k) clearance for its GammaCore system, now cleared for adjunctive use for the preventive treatment of cluster headaches in adult patients. The post ElectroCore wins 5-year GammaCore federal supply deal appeared first on MassDevice.
Source: Mass Device - Category: Medical Devices Authors: Tags: Business/Financial News Neurological electroCore Source Type: news

Related Links:

People stricken with COVID-19 exhibit a wide range of symptoms. Some are barely affected while others suffer dire consequences. People with asthma are in particular danger, as SARS-CoV-2 is a respiratory virus that can make breathing even more diffic...
Source: Medgadget - Category: Medical Devices Authors: Tags: Cardiology Critical Care Emergency Medicine Neurology Pain Management Public Health Source Type: blogs
Conclusions: When comparing nVNS with sham, no statistically significant differences were found with regards to the primary endpoint of pain freedom at 120 minutes, although differences were found with various secondary endpoints and post hoc analysis. nVNS is likely a safe alternative to medications.
Source: The Neurologist - Category: Neurology Tags: Critically Appraised Topics Source Type: research
CONCLUSIONS: The present study does not support an acute effect of nVNS on descending pain inhibition, pain intensity perception or supraspinal nociception in healthy adults. However, there was a small effect on pain unpleasantness during nVNS, suggesting that nVNS may preferentially act on affective, not somatosensory pain components. PMID: 32592516 [PubMed - as supplied by publisher]
Source: Headache - Category: Neurology Authors: Tags: Headache Source Type: research
Experimental and clinical data strongly support vagus nerve stimulation (VNS) as a novel treatment in migraine. Vagus nerve stimulation acutely suppresses cortical spreading depression (CSD) susceptibility, an experimental model that has been used to screen for migraine therapies. However, mechanisms underlying VNS efficacy on CSD are unknown. Here, we interrogated the central and peripheral mechanisms using VNS delivered either invasively (iVNS) or noninvasively (nVNS) in male Sprague-Dawley rats. Cortical spreading depression susceptibility was evaluated 40 minutes after the stimulation. iVNS elevated the electrical CSD ...
Source: Pain - Category: Anesthesiology Tags: Research Paper Source Type: research
ConclusionsCervical nVNS is effective for acute pain relief for migraine and cluster headache.Systematic review registrationPROSPERO registration number CRD42019126009.
Source: Neuromodulation: Technology at the Neural Interface - Category: Biotechnology Authors: Tags: Clinical Research Source Type: research
Conclusion ANT-DBS and VNS may influence epilepsy-associated chronic headache in different ways. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text
Source: Journal of Neurological Surgery Part A: Central European Neurosurgery - Category: Neurosurgery Authors: Tags: Case Report Source Type: research
Migraine is a prevalent neurological disease that is characterized by unpredictable episodic attacks of intense head pain. The underlying pathology involves sensitization and activation of the trigeminal system. Although non-invasive vagus nerve stimulation (nVNS) is recommended for the treatment of migraine, the abortive mechanism of action is not well-understood. The goal of this study was to compare the ability of nVNS and sumatriptan to inhibit trigeminal activation in two animal models of episodic migraine and to investigate the receptor mechanism of action of nVNS. Nocifensive head withdrawal response was investigate...
Source: Frontiers in Neurology - Category: Neurology Source Type: research
AbstractPurpose of ReviewScientists have reported that pain is always created by the brain. This may not be entirely true. Pain is not only a sensory experience, but also can be associated with emotional, cognitive, and social components. The heart is considered the source of emotions, desire, and wisdom. Therefore, the aim of this article was to review the available evidence about the role of the heart in pain modulation.Recent FindingsDr. Armour, in 1991, discovered that the heart has its “little brain” or “intrinsic cardiac nervous system.” This “heart brain” is composed of approximat...
Source: Current Pain and Headache Reports - Category: Neurology Source Type: research
ConclusionOur results suggest that taVNS at 1 Hz can significantly modulate activity/connectivity of brain regions associated with the vagus nerve central pathway and pain modulation system, which may shed light on the neural mechanisms underlying taVNS treatment of migraine.
Source: NeuroImage: Clinical - Category: Radiology Source Type: research
Purpose of review Cluster headache stands among the worst debilitating pain conditions. Available treatments for cluster headache have often disabling side effects, are not tolerated, or are ineffective. The management of drug-refractory chronic forms is challenging. New treatments are warranted and reported here. Recent findings In cluster headache acute treatment, delivery systems like Demand Valve Oxygen or nonrebreather-type masks could enhance the effectiveness of inhaled oxygen therapy. Noninvasive vagus nerve stimulation relieves cluster headache pain at short-term in episodic patients. Sphenopalatine ganglion ...
Source: Current Opinion in Neurology - Category: Neurology Tags: HEADACHE: Edited by Messoud Ashina and Henrik Winther Schytz Source Type: research
More News: Brain | Contracts | Government | Headache | India Health | International Medicine & Public Health | Medical Devices | Migraine | Neurology | Pain | Skin | Vagus Nerve Stimulation Therapy