Progress in the understanding of polycystic kidney disease

Progress in the understanding of polycystic kidney diseaseProgress in the understanding of polycystic kidney disease, Published online: 03 January 2019; doi:10.1038/s41581-018-0108-1The function of polycystin proteins and the pathogenesis of autosomal dominant polycystic kidney disease (ADPKD) are not well understood. Studies published in 2018 made important contributions to the understanding of genetic mechanisms, the structure of the polycystin complex and the roles of G-protein signalling and the immune system in ADPKD.
Source: Nature Reviews Nephrology - Category: Urology & Nephrology Authors: Source Type: research