Breath test to detect multiple cancers early begins large trial
A breathalyzer designed to detect multiple cancers early is being tested in the UK.
Publication date: Available online 17 March 2019Source: Gynecologic Oncology ReportsAuthor(s): Roberta Villa, Jacopo Azzollini, Bernard Peissel, Siranoush ManoukianAbstractBackgroundMayer-Rokitansky-Kuster-Hauser syndrome (MRKHS) is a congenital disorder of yet unknown etiology, characterized by agenesis/hypoplasia of the müllerian duct system. The occurrence of ovarian cancer (OC) in MRKHS is rare, with
Chemotherapy overdose may be avoided in obese patients with breast cancer using a tailored dosing strategy.Annals of Oncology
CONCLUSIONS Mukonal inhibited the growth of human CNE1 nasopharyngeal carcinoma cells in vitro. PMID: 30877718 [PubMed - in process]
Publication date: Available online 16 March 2019Source: The Annals of Thoracic SurgeryAuthor(s): Ya-Fu Cheng, Bing-Yen Wang, Hui-Shan Chen
It felt like Sarah Hanan's life had "come to a screeching halt", but it was only the start of her journey.
Publication date: Available online 16 March 2019Source: Journal of Microbiological MethodsAuthor(s): Himadri Tanaya Behera, Anjani Kumar Upadhyay, Vishakha Raina, Lopamudra RayAbstractOptimization of media composition for microbial growth is crucial particularly in industrial processes to obtain the desired end product. The waste from sea food industries includes the non-edible parts of shrimp, crabs and prawns which are rich in chitin as the major cause of pollution in coastal areas. Chitin degradation is carried out chemically. It can be degraded biologically also, particularly using microorganisms resulting in chitoolig...
Publication date: Available online 16 March 2019Source: Pesticide Biochemistry and PhysiologyAuthor(s): Darpan Raghav, Susobhan Mahanty, Krishnan RathinasamyAbstractKaranjin, a furanoflavonol from Pongamia pinnata L is used in agricultural practices for its pesticidal, insecticidal and acaricidal activities. It is commercially available as a bio-pesticide targeting a wide variety of pests. The present study was intended to evaluate the biochemical interactions of karanjin with bovine serum albumin (BSA) and study its toxicological effects on mammalian and bacterial cell lines. Karanjin bound to BSA at a single site with a ...
In conclusion, by using IBC as a chemical probe, we provide new characteristics of methuosis-like cell death. Inducing methuosis-like cell death may represent a novel strategy to combat leukemia.
Publication date: 16 March 2019Source: New Scientist, Volume 241, Issue 3221Author(s): Linda GeddesFor years, we were told to slather on sunscreen to prevent skin cancer. But does blocking out the sun do us more harm than good? Linda Geddes investigates
This study investigated treatment outcomes and prognostic factors of survival in CEC patients undergoing definitive radiotherapy or concurrent chemoradiotherapy (CCRT). Ninety-one CEC patients were treated by intensity-modulated radiation therapy (IMRT) and three-dimensional conformal radiation therapy (3DCRT) between July 2007 and September 2017. The mean prescription dose was 64 Gy (range 54-70 Gy) delivered as 1.8-2.2 Gy per fraction per day, 5 days a week. Out of 91 patients, 34 received concurrent cisplatin-based chemotherapy (CT) including 18 patients who also received neoadjuvant CT. Overall survival (OS), locoregio...