The Silent Shame of Male Infertility

Bradley Goldman has filled out a size large T-shirt his whole adult life. As a bodybuilder, he knew that a steady stream of lean, bland proteins, heavy weights and steroids would make his muscles pop. But over the past six months, Goldman, a fitness and nutrition consultant in Los Angeles, has watched his jacked physique soften and shrink. “I cracked a couple of weeks ago, and I had to buy a shirt a whole size smaller,” he says. He tried it on for his wife Brittany, and it hung loose on his frame. “I just kind of shook my head,” he says. He knew she saw the changes too. Goldman, now 30, began taking steroids at 18. He’d heard they could interfere with fertility–steroids can shut down the body’s natural production of testosterone–but like many young men, he was more concerned with not having babies than with having them. Now he and his wife are trying to get pregnant, and though he gave up steroids two years ago, it seems the damage is done. When he got a semen analysis last March, his sperm count came back a flat zero. “It was earth-shattering,” he says. He started taking fertility drugs to help his testicles recover. But three months later, he still had no sperm. He’d been injecting himself with testosterone because his body could no longer produce it naturally, but his doctor recommended he stop in order to make the fertility drugs more effective. Now his sperm count is slowly climbing, but his sex drive has...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized fertility Research Source Type: news

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We present the case of a 56-year-old female presenting with bilateral foot pain. Imaging reveals symmetrical abductor digiti minimi atrophy associated with bilateral plantar fasciitis. These appearances are well demonstrated on both magnetic resonance imaging and ultrasound.
Source: The Journal of Foot and Ankle Surgery - Category: Orthopaedics Source Type: research
This study aimed to evaluate the therapeutic effect of folic acid (FA) on diabetic retinopathy (DR) in a genetic mouse model of obese type 2 diabetes mellitus (T2D). C57BL/KsJ-db/db(db/db) T2D mice were divided into control, FA, metformin (MET), and FA plus MET groups (n = 10/group). Serum levels of glucose, glycated hemoglobin, and insulin were determined weekly. The retinal thickness was measured using optical coherence tomography (OCT) at 4 weeks after treatments. The retinal expression and serum levels of vascular formation, inflammation, and oxidative stress-associated molecules were examined. Our results demonstrated...
Source: Ophthalmic Research - Category: Opthalmology Source Type: research
Publication date: June 2019Source: Journal of Functional Foods, Volume 57Author(s): Han-Jun Kim, Eun-Ji Choi, Hyo Sung Kim, Chan-Woong Choi, Sik-Won Choi, Sun-Lim Kim, Woo-Duck Seo, Sun Hee DoAbstractPostmenopausal obesity is becoming a serious global health concern. Soyasaponin Ab (SA) inhibits adipocyte differentiation; however, the preventive and therapeutic potential of SA in postmenopausal obesity has not been clearly established. Here, we investigated the anti-obesity effects of SA in postmenopausal obesity in vitro and in vivo. SA inhibited adipocytic differentiation of 3T3-L1 cells and reduced lipid accumulati...
Source: Journal of Functional Foods - Category: Nutrition Source Type: research
This study aimed to investigate the effect of stevioside on fatty liver. Rats with hyperlipidemic fatty liver were treated with 75–150 mg/kg stevioside for 6 weeks. After oral administration of stevioside, the levels of serum and hepatic lipids and degree of hepatic steatosis were decreased. Stevioside treatment increased the expressions of hepatic peroxisome proliferator-activated receptor (PPAR)α and carnitine palmitoyltransferase-1A proteins and decreased the expressions of hepatic sterol regulatory element-binding protein-1c, fatty acid synthase and diacylglycerol acyltransferase proteins. Following tre...
Source: Journal of Functional Foods - Category: Nutrition Source Type: research
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Source: Journal of the American Dietetic Association - Category: Nutrition Tags: From the Academy Source Type: research
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Source: Journal of the American Dietetic Association - Category: Nutrition Tags: From the Academy Source Type: research
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Source: Journal of the American Dietetic Association - Category: Nutrition Authors: Tags: Practice Applications Source Type: research
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Source: Annals of Nutrition and Metabolism - Category: Nutrition Source Type: research
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Source: Annals of Nutrition and Metabolism - Category: Nutrition Source Type: research
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