High x-ray dose surges cancer risk in obese patients

The elevated radiation dose needed to acquire x-ray images of obese patients...Read more on AuntMinnie.comRelated Reading: 'Fatter' phantoms expose radiation's burden on the obese Study: X-ray radiation dose to obese may be higher than thought
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news

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Americans consume about 150 pounds of milk and eat nearly 40 pounds of cheese and 20 pounds of ice cream per person per year, according to data from the Department of Agriculture. Yogurt and butter intakes are lower, but growing. But should the dairy we’re consuming be low-fat or full-fat? That debate has become increasingly divisive, and for good reason: not all dairy is created equal. Dairy fat and cardiovascular disease Some of the most substantial dairy research has been done in the context of the Dietary Approaches to Stop Hypertension (DASH) diet, which has been shown, among other benefits, to reduce blood pres...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Cancer Diet and Weight Loss Health Healthy Eating Heart Health Source Type: blogs
In this study, AT1-AAs were detected in the sera of patients with peripheral arterial disease (PAD) and the positive rate was 44.44% vs. 17.46% in non-PAD volunteers. In addition, analysis showed that AT1-AAs level was positively correlated with PAD. To reveal the causal relationship between AT1-AAs and vascular aging, an AT1-AAs-positive rat model was established by active immunization. The carotid pulse wave velocity was higher, and the aortic endothelium-dependent vasodilatation was attenuated significantly in the immunized rats. Morphological staining showed thickening of the aortic wall. Histological examination showe...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
ConclusionsDifferential disease classification among men who may be recommended to undergo and then consider whether to accept a prostate biopsy leads to inaccurate identification of prostate cancer risk factors. Imputing a man’s prostate cancer status reduces detection bias. Covariate adjustment does not address the problem of outcome misclassification. Cohorts evaluating incident prostate cancer should collect longitudinal screening and biopsy data to adjust for this potential bias.
Source: Cancer Epidemiology - Category: Cancer & Oncology Source Type: research
AbstractCertain patient populations (pregnancy, cancer, renal impairment, and obesity) may be at higher risk of adverse events during low molecular weight heparin (LMWH) therapy and may benefit from anti-Xa monitoring. Yet, evidence supporting a standardized approach to anti-Xa monitoring correlated to clinical outcomes is lacking. Patients with at least one documented anti-Xa level and receiving LMWH within a 6-month period were identified. In a 6-month period, 224 adult LMWH patients with 359 anti-Xa levels were identified. Anti-Xa monitoring was most commonly performed in patients with active cancer receiving venous thr...
Source: Journal of Thrombosis and Thrombolysis - Category: Hematology Source Type: research
Publication date: Available online 18 October 2019Source: Molecular MetabolismAuthor(s): Matthieu Lacroix, Romain Riscal, Giuseppe Arena, Laetitia Karine Linares, Laurent Le CamAbstractBackgroundThe TP53 gene is one of the most commonly inactivated tumor suppressors in human cancers. p53 functions during cancer progression have been linked to a variety of transcriptional and non-transcriptional activities that lead to the tight control of cell proliferation, senescence, DNA repair, and cell death. However, converging evidence indicates that p53 also plays a major role in metabolism in both normal and cancer cells.Scope of ...
Source: Molecular Metabolism - Category: Endocrinology Source Type: research
Publication date: 19–25 October 2019Source: The Lancet, Volume 394, Issue 10207Author(s): Evelien Dekker, Pieter J Tanis, Jasper L A Vleugels, Pashtoon M Kasi, Michael B WallaceSummarySeveral decades ago, colorectal cancer was infrequently diagnosed. Nowadays, it is the world's fourth most deadly cancer with almost 900 000 deaths annually. Besides an ageing population and dietary habits of high-income countries, unfavourable risk factors such as obesity, lack of physical exercise, and smoking increase the risk of colorectal cancer. Advancements in pathophysiological understanding have increased the array of treatme...
Source: The Lancet - Category: General Medicine Source Type: research
Conditions:   Cancer;   Overweight and Obesity Intervention:   Behavioral: eHealth Intervention Sponsor:   University of Alabama at Birmingham Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
by Mathias J. Gerl, Christian Klose, Michal A. Surma, Celine Fernandez, Olle Melander, Satu M ännistö, Katja Borodulin, Aki S. Havulinna, Veikko Salomaa, Elina Ikonen, Carlo V. Cannistraci, Kai Simons Obesity is associated with changes in the plasma lipids. Although simple lipid quantification is routinely used, plasma lipids are rarely investigated at the level of individual molecules. We aimed at predicting different measures of obesity based on the plasma lipidome in a large population cohor t using advanced machine learning modeling. A total of 1,061 participants of the FINRISK 2012 population cohort were ra...
Source: PLoS Biology: Archived Table of Contents - Category: Biology Authors: Source Type: research
AbstractAlgeria, like all emerging countries, has been going through a health transition over the past 30  years or so, characterized by a drop in mortality rates, an increase in life expectancy and a change in the causes of death in favor of chronic non-communicable diseases. In the past, the country mainly faced infectious diseases such as typhoid, cholera and malaria. The prevalence of the latter ha s been significantly reduced thanks to the many social health and vaccination programs undertaken by the health authorities. As a result of this epidemiological transition, we are witnessing a growing increase in the in...
Source: Internal and Emergency Medicine - Category: Emergency Medicine Source Type: research
Publication date: Available online 16 October 2019Source: Genes &DiseasesAuthor(s): Prasanna K. SanthekadurAbstractFructose, an essential biomolecule is a major ingredient of the modern diet across the globe. Excess consumption of fructose may be a key driver of many serious diseases such as obesity, heart diseases, type 2 diabetes and cancer. Understanding the metabolism of fructose, molecular mechanisms of its toxic nature will aid in the treatment of various diseases including cancer.
Source: Genes and Diseases - Category: Genetics & Stem Cells Source Type: research
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