Association of human leukocyte antigens ‐DQB2/DPA1/DPB1 polymorphism and pulmonary tuberculosis in the Chinese Uygur population

ConclusionThese results suggested that the functional HLA ‐DQB2 rs7453920 G>A polymorphism may contribute to the genetic susceptibility to TB. Nevertheless, the results were based on a limited sample size, and larger well ‐designed studies are expected to confirm these preliminary findings.
Source: Molecular Genetics & Genomic Medicine - Category: Genetics & Stem Cells Authors: Tags: ORIGINAL ARTICLE Source Type: research

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In conclusion, it seems essential to implement effective educational and informative activities targeted to parents to reinforce positive attitudes toward vaccinations. PMID: 31705322 [PubMed - as supplied by publisher]
Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research
Two large public image datasets commonly used to train artificial intelligence...Read more on AuntMinnie.comRelated Reading: AI needs robust clinical evaluation in healthcare AI may help improve sensitivity of ED chest x-ray reads AI model could speed up pneumonia diagnosis in ED Are studies on AI for tuberculosis really valid? AI tops recent imaging informatics highlights
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
[The Conversation Africa] Important gains have been made in the global fight against tuberculosis (TB). Each year, fewer people are being diagnosed with the disease. The recent World Health Organisation (WHO) global TB report, which gathers data from 202 countries and territories, shows a 6.3% reduction in the number of new TB infections between 2015 and 2018. This trend of decreasing incidence is also evident in Africa, where it fell from 275 per 100 000 people in 2015 to 231 per 100 000 in 2018.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
Conclusions: The spatial clusters of TB incidence shifted to the rural region and the fringe of the new urban area of Nanchang. Targeted management strategies for urban migrants in the process of urbanization should be strengthened.
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
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Source: Infectious Diseases - Category: Infectious Diseases Authors: Source Type: research
Conference abstracts
Source: The Aspergillus Website - updates - Category: Respiratory Medicine Authors: Source Type: news
BCG stimulation promotes dendritic cell proliferation and expression of VDR and CYP27B1 in vitamin D‑deficient mice. Mol Med Rep. 2019 Oct 30;: Authors: Yang H, Zhang H, Li Y, Xiang L, Liu J Abstract Vitamin D deficiency may lead to an increased risk of tuberculosis. In the present study, the effects of Mycobacterium tuberculosis (Mtb) infection on dendritic cells (DCs) derived from vitamin D‑deficient mice or normal control mice were investigated. A vitamin D‑deficient mouse model was established, and bone marrow‑derived DCs (BMDCs) were isolated and treated with GM‑CSF and in...
Source: Molecular Medicine Reports - Category: Molecular Biology Tags: Mol Med Rep Source Type: research
ConclusionsThis study shows that the alveolar microbiota profile in BAL samples from TB and IP patients, representing infectious and non-infectious lung diseases, respectively, is characterized by decreased diversity.
Source: Microbial Pathogenesis - Category: Infectious Diseases Source Type: research
Publication date: Available online 8 November 2019Source: Respiratory InvestigationAuthor(s): Lucia Vietri, Annalisa Fui, Laura Bergantini, Miriana d’Alessandro, Paolo Cameli, Piersante Sestini, Paola Rottoli, Elena BargagliAbstractSerum amyloid A is an acute-phase protein with multiple immunological functions. Serum amyloid A is involved in lipid metabolism, inflammatory reactions, granuloma formation, and cancerogenesis. Additionally, serum amyloid A is involved in the pathogenesis of different autoimmune lung diseases. The levels of serum amyloid A has been evaluated in biological fluids of patients with different...
Source: Respiratory Investigation - Category: Respiratory Medicine Source Type: research
Publication date: Available online 9 November 2019Source: Respiratory Medicine Case ReportsAuthor(s): Wajahat Dawood, De La Garza Henriette, Gloria Iliescu, Cesar Moran, Horiana Grosu
Source: Respiratory Medicine Case Reports - Category: Respiratory Medicine Source Type: research
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