Cancers, Vol. 11, Pages 35: Potential for Improvements in Robustness and Optimality of Intensity-Modulated Proton Therapy for Lung Cancer with 4-Dimensional Robust Optimization

Conclusion: The incorporation of respiratory motion, along with setup and range uncertainties, into robust optimization, has the potential to improve the resilience of target and normal tissue dose distributions in IMPT plans in the face of the uncertainties considered. Moreover, it improves the optimality of plans compared to PTV-based optimization as well as 3DRO.

Source: Cancers - January 1, 2019 Category: Cancer & Oncology Authors: Shuaiping Ge Xiaochun Wang Zhongxing Liao Lifei Zhang Narayan Sahoo Jinzhong Yang Fada Guan Radhe Mohan Tags: Article Source Type: research