Selective efficacy of zoledronic acid on metastasis in a patient‐derived orthotopic xenograph (PDOX) nude‐mouse model of human pancreatic cancer

ConclusionsThe results of the present study indicate that ZA can selectively target metastasis in a pancreatic cancer PDOX model and that the combination of ZA and GEM should be evaluated clinically in the near future for this highly treatment‐resistant disease. J. Surg. Oncol. 2014;9999:XX–XX. © 2014 Wiley Periodicals, Inc.

Source: Journal of Surgical Oncology - November 14, 2014 Category: Cancer & Oncology Authors: Yukihiko Hiroshima, Ali A. Maawy, Matthew H.G. Katz, Jason B. Fleming, Michael Bouvet, Itaru Endo, Robert M. Hoffman Tags: Research Article Source Type: research