Cerebrospinal fluid penetration of very high-dose meropenem: a case report

Standard dosing of meropenem (2 g t.i.d.) produces CSF concentrations of only 1 –2 mg/L which is inferior to the clinical breakpoint for most Gram-negative bacteria. There is therefore concern that dosing must ...

Source: Annals of Clinical Microbiology and Antimicrobials - December 29, 2018 Category: Microbiology Authors: Thomas Kerz, Friederike D. von Loewenich, Jason Roberts, Axel Neulen and Florian Ringel Tags: Case Report Source Type: research