CME Exam: Adult-Onset Atopic Dermatitis

Publication date: January 2019Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 7, Issue 1Author(s):
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research

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Publication date: Available online 21 March 2019Source: Regulatory Toxicology and PharmacologyAuthor(s): David A. Basketter, Joe Huggard, Ian KimberAbstractThe toxicology of fragrance materials is largely well understood. Although most are benign, a minority have the potential to cause adverse health effects, notably allergic contact dermatitis resulting from skin sensitisation. As a consequence, industry guidelines have banned certain materials and strictly limited the use of others. Recently, data have been published that have been interpreted to suggest that inhalation of fragrances is associated with the occurrence of ...
Source: Regulatory Toxicology and Pharmacology - Category: Toxicology Source Type: research
The rising prevalence of allergies represents an increasing socioeconomic burden. A detailed understanding of the immunological mechanisms that underlie the development of allergic disease, as well as the processes that drive immune tolerance to allergens, will be instrumental in designing therapeutic strategies to treat and prevent allergic disease. Improved characterization of individual patients through the use of specific biomarkers and improved definitions of disease endotypes are paving the way for the use of targeted therapeutic approaches for personalized treatment. Allergen-specific immunotherapy and biologic ther...
Source: Journal of Clinical Investigation - Category: Biomedical Science Authors: Source Type: research
Conclusion: A rapid acetylator status might predispose to ACD without influencing other features of this disease.
Source: Indian Journal of Dermatology - Category: Dermatology Authors: Source Type: research
Conclusions: In conclusion, our report shows that cooked onion can induce severe allergic reactions, suggesting the presence of thermostable components. Moreover, we applied for the first time a B-cell-based approach to the diagnosis of food allergy. This latter approach might also be applied to other allergic conditions. PMID: 30858787 [PubMed]
Source: Advances in Dermatology and Allergology - Category: Dermatology Tags: Postepy Dermatol Alergol Source Type: research
Conditions:   Eczema Atopic Dermatitis;   Eczema;   Eczema, Infantile;   Food Allergy Intervention:   Other: Skin barrier protection in the first 2 months of life Sponsor:   University College Cork Not yet recruiting
Source: - Category: Research Source Type: clinical trials
Atopic dermatitis is a chronic inflammatory skin disorder, whose symptoms and severity grossly depend on individual trigger factors. The majority of patients are satisfactorily treated with emollients together...
Source: Clinical and Molecular Allergy - Category: Allergy & Immunology Authors: Tags: Case Report Source Type: research
Atopic dermatitis (AD) is a chronic, predominantly type 2 inflammatory skin disease that affects up to 10% of adults and 20% of children [1 –5]. Moderate-to-severe AD is characterized by extensive eczematous lesions, pronounced persistent, severe itch [6–8], substantial pain and discomfort [9–12], and is frequently associated with other type 2 (atopic/allergic) comorbidities, e.g. asthma, allergic rhinitis, chronic rhinosinusitis with nasal polyposis (CRSwNP), eosinophilic esophagitis, and food allergies [8,13–15], and a significant disease burden, e.g.
Source: Journal of Dermatological Science - Category: Dermatology Authors: Source Type: research
AbstractPurpose of ReviewStaphylococcus aureus (S. aureus) is correlated with the development of persistent severe inflammatory disease of the upper airway including chronic rhinosinusitis with nasal polyps (CRSwNP). The presence ofS. aureus is associated with atopic disease including allergic rhinitis and atopic dermatitis and is associated with poor outcomes.Recent FindingsSeveral different strains ofS. aureus generate different toxins and gene products that can account for organism pathogenicity.S. aureus bacteria and its antigens shape the bacterial and fungal microbiome and the mucosal niche which generates host respo...
Source: Current Allergy and Asthma Reports - Category: Allergy & Immunology Source Type: research
Publication date: Available online 8 March 2019Source: Veterinary ParasitologyAuthor(s): Wakako Yonetake, Takeshi Fujii, Masaya Naito, Andrew Hodge, Steven Maeder, Douglas RuggAbstractThe efficacy of a single application of a new topical formulation containing selamectin plus sarolaner (Revolution® Plus / Stronghold® Plus, Zoetis) was evaluated against fleas and ticks infesting cats enrolled as veterinary patients in two field studies conducted in Japan and against Haemaphysalis longicornis ticks on cats in a laboratory study.In the laboratory study, sixteen cats were ranked based on pre-treatment tick counts and a...
Source: Veterinary Parasitology - Category: Veterinary Research Source Type: research
AbstractCosmetics and skin care products for neonates and infants are considered as ‘‘hypoallergenic’’, “tested” or ‘‘safe’’. Nevertheless, the prevalence of haptens in these products is a matter of concern, since allergic contact dermatitis in children is gaining an importance. We aimed to assess the prevalence of haptens in cosmetics designed for children youn ger than 1 year. To identify haptens, the components of the cosmetics listed on packaging were compared with substances from European baseline series, Cosmetics series and Fragrance series. Survey com...
Source: Clinical and Translational Allergy - Category: Allergy & Immunology Source Type: research
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