Prolonged Beta-Lactam Provocation Challenges in Children: Do Extended Protocols Offer Any Benefit?

Publication date: January 2019Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 7, Issue 1Author(s): Sigrid Payne DaVeiga, Francesca Saretta
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research

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Conclusions: tTGIgA were increasingly tested, while the rate of positive results decreased in recent years, possibly reflecting the impact of current alimentary trends on clinical practice. Associated autoimmune disease was frequently found in CD. High levels of tTGIgA accurately predicted CD diagnosis. WA was rarely investigated and deserves more attention, in particular in children with atopic background. WA does not seem to be associated with CD.Int Arch Allergy Immunol
Source: International Archives of Allergy and Immunology - Category: Allergy & Immunology Source Type: research
European populations are overrepresented in genetic and genomic studies, contributing to healthcare inequities.Medscape Medical News
Source: Medscape Allergy Headlines - Category: Allergy & Immunology Tags: Internal Medicine News Source Type: news
CONCLUSIONS: The technique in our study is simple and reproducible. Azelastine could inhibit both EFS and methoxamine-induced nasal mucosal contractions in vitro. This study highlights that although azelastine nasal spray is often used in treating allergic rhinitis to improve symptoms, nasal obstruction may be not relieved immediately due to the anti-sympathetic effect of azelastine. PMID: 30887967 [PubMed - as supplied by publisher]
Source: Rhinology - Category: ENT & OMF Tags: Rhinology Source Type: research
The recall was initiated after it was discovered that a package of 10-ounce Original Potato Chips dated 10 AUG 2019 did not contain Original Potato Chips but instead contained Cheddar and Sour Cream Potato Chips which contain milk. Subsequent investigation indicates the problem was caused by a temporary breakdown in the company's production and packaging processes which may have affected 660 bags of 10-ounce Original Potato Chips.
Source: Food and Drug Administration - Category: Food Science Source Type: news
Publication date: Available online 21 March 2019Source: Regulatory Toxicology and PharmacologyAuthor(s): David A. Basketter, Joe Huggard, Ian KimberAbstractThe toxicology of fragrance materials is largely well understood. Although most are benign, a minority have the potential to cause adverse health effects, notably allergic contact dermatitis resulting from skin sensitisation. As a consequence, industry guidelines have banned certain materials and strictly limited the use of others. Recently, data have been published that have been interpreted to suggest that inhalation of fragrances is associated with the occurrence of ...
Source: Regulatory Toxicology and Pharmacology - Category: Toxicology Source Type: research
Century Snacks, LLC of Commerce, CA is recalling all packages of 3-oz. and 5.75-oz. SNAK CLUB HONEY BLISS NUT MIX due to undeclared MILK. People who have an allergy or severe sensitivity to MILK run the risk of serious or life-threatening allergic reaction if they consume these products.
Source: Food and Drug Administration - Category: Food Science Source Type: news
Targeted therapy and immunotherapy are showing promising longer-term outcomes in metastatic melanoma. Dr Weber reviews two new studies.Medscape Oncology
Source: Medscape Allergy Headlines - Category: Allergy & Immunology Tags: Hematology-Oncology Commentary Source Type: news
In this study, a systematic literature review of allergy-like reactions caused by methylene blue dye following laparoscopic chromopertubation was conducted. A search was conducted in PUBMED, Web of Science, and Scopus from inception until June, 2018, using the terms: “methylene blue”, “complication”, “allergic”, “hypersensitive”, “lung/pulmonary edema”,” methemoglobinemia”, “anaphylactic shock”, “chromopertubation”, “pertubation”, “laparoscopic”, and “laparoscopy”. Ultimately, the eligibility ...
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - Category: OBGYN Source Type: research
A new U.S. study of groups of Latino youth with asthma sheds light on potential health disparities. Puerto Rican children were less likely than Mexican kids to use asthma inhalers regularly, researchers found.Reuters Health Information
Source: Medscape Allergy Headlines - Category: Allergy & Immunology Tags: Pulmonary Medicine News Source Type: news
AbstractAccumulation of bile acids (BAs) contributes significantly to the pathogenesis of primary biliary cholangitis (PBC). Here, we sought to systematically characterize the serum and fecal BA profiles and the linkage between BAs and gut microbiota in PBC. The serum and fecal BAs were compared between 65 UDCA treatment-naive PBC and 109 healthy controls using UPLC-MS in cross-sectional study. In a prospective study, a subgroup of patients was enrolled for BA and microbiota analysis before and after UDCA therapy. BA compositions in serum and feces significantly differed between treatment-naive PBC and controls. Particular...
Source: Clinical Reviews in Allergy and Immunology - Category: Allergy & Immunology Source Type: research
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