Overexpression of indoleamine 2,3-dioxygenase correlates with regulatory T cell phenotype in acute myeloid leukemia patients with normal karyotype.
Conclusion: Higher IDO expression in CN-AML patients may be associated with an increased Treg phenotype which may promote disease progression and lead to poor prognosis of CN-AML patients.
PMID: 30588466 [PubMed]
Source: Blood Research - Category: Hematology Tags: Blood Res Source Type: research
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