Overexpression of indoleamine 2,3-dioxygenase correlates with regulatory T cell phenotype in acute myeloid leukemia patients with normal karyotype.

Conclusion: Higher IDO expression in CN-AML patients may be associated with an increased Treg phenotype which may promote disease progression and lead to poor prognosis of CN-AML patients. PMID: 30588466 [PubMed]
Source: Blood Research - Category: Hematology Tags: Blood Res Source Type: research