Update on postprandial hyperglycemia: The pathophysiology, prevalence, consequences and implications of treating diabetes

Publication date: Available online 27 December 2018Source: Revista Clínica Española (English Edition)Author(s): P.J. Pinés Corrales, V. Bellido Castañeda, F.J. Ampudia-BlascoAbstractTo achieve appropriate glycaemic control, postprandial and baseline hyperglycemia should be reduced. Various epidemiological studies have suggested an association between fluctuations in postprandial blood glucose and cardiovascular risk. However, studies of interventions performed to date have not shown that selective control of postprandial hyperglycemia is associated with cardiovascular benefits. Accordingly, an appropriate combination of drugs that control both baseline and postprandial hyperglycemia (individually based on each patient's characteristics) is the best strategy for achieving good glycaemic control. This review seeks to impart to clinicians the concept of postprandial hyperglycemia, analysing its causes, how to measure it, its prevalence, its consequences and, ultimately, the available therapeutic strategies for the preferential control of the postprandial hyperglycemia along with baseline hyperglycemia.ResumenPara alcanzar un control glucémico adecuado, la hiperglucemia posprandial y basal debe reducirse. Diversos estudios epidemiológicos sugieren una asociación de las fluctuaciones de glucemia posprandial con el riesgo cardiovascular. Sin embargo, los estudios de intervención realizados hasta el momento no demuestran que el control selectivo de la hiperglucemia posprandi...
Source: Revista Clinica Espanola - Category: Internal Medicine Source Type: research