Novel Oral Anticoagulants in Peripheral Artery Disease. Current Evidence.

CONCLUSION: For the time being, novel oral anticoagulants in combination with aspirin may provide an alternative treatment in PAD, however, it is deemed necessary to identify patient subgroups who will benefit the most. PMID: 30585539 [PubMed - as supplied by publisher]
Source: Current Pharmaceutical Design - Category: Drugs & Pharmacology Authors: Tags: Curr Pharm Des Source Type: research

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Publication date: Available online 17 February 2020Source: Surgery (Oxford)Author(s): Tristan E. McMillan, Timothy Gardner, Alan J. JohnstoneAbstractTourniquets have been around for many years, providing surgeons with a bloodless operative field and saving lives in the pre-hospital care of major limb trauma. However, their use does come with risk. It is therefore extremely important that we, as surgeons, fully understand the physiological influence they impose on patients, the complications associated with their use and, moreover, how to minimize the incidence of these complications. Most tourniquets are now electronically...
Source: Surgery (Oxford) - Category: Surgery Source Type: research
Where do we stand in the prevention and treatment of cerebral small vessel diseases? This review highlights current knowledge gaps and summarizes ongoing trials.Stroke
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Neurology & Neurosurgery Journal Article Source Type: news
Condition:   Spatial Neglect Interventions:   Behavioral: Optokinetic stimulation and cueing-based reading therapy (OKS-READ);   Behavioral: General neuropsychological treatment Sponsor:   University of Luebeck Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Stroke;   Prevention Interventions:   Drug: Rivaroxaban 2.5 Mg Oral Tablet;   Drug: Rivaroxaban placebo tablets Sponsor:   Mazandaran University of Medical Sciences Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Anxiety Disorders;   Oral Disease;   Periodontal Diseases;   Periodontal Attachment Loss;   Periodontal Pocket;   Periodontal Inflammation;   Gingival Recession;   Gingival Bleeding;   Gingival Diseases;   Bruxism;   Caries,Dental;   Health Care Seeking Behavior;   Healt h Care Utilization;   Self-Perception Intervention:   Sponsor:   Ain Shams University Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Whole organs are difficult to study in minute detail, as they have to be sliced into extremely thin sections to map out their interior. CT and magnetic resonance imaging help to an extent, but researchers at the Helmholtz Zentrum München, Ludwig...
Source: Medgadget - Category: Medical Devices Authors: Tags: Materials News Radiology Surgery Source Type: blogs
Conclusion: Patients with prior stroke may be the preferred group for LAAC regardless of the presence or absence of contraindications for anticoagulant therapy.
Source: Cerebrovascular Diseases - Category: Neurology Source Type: research
Abstract Oral anticoagulants (OAC) are widely used for prevention of systemic thromboembolism, including the reduction of the risk of stroke in patients with atrial fibrillation (AF) and prosthetic heart valves. There is also an increasing population of patients who require not only OACs, but also double antiplatelet therapy (DAPT). A typical example is a patient with AF and stable coronary artery disease or acute coronary syndrome (ACS), treated by percutaneous coronary intervention (PCI). In recent years, with the introduction of NOACs, triple or dual therapy has become safer. Regardless of these indications for...
Source: Polish Heart Journal - Category: Cardiology Authors: Tags: Kardiol Pol Source Type: research
Abstract PURPOSE: The purpose of this study is to report on the effect of using CHA2DS2VASc (congestive heart failure, hypertension, age ≥75 years [doubled], type 1 or type 2 diabetes mellitus, stroke or transient ischemic attack or thromboembolism [doubled], vascular disease [prior myocardial infarction, peripheral artery disease, or aortic plaque], age 65-75 years, sex category [female]) rather than CHADS2 (congestive heart failure, hypertension, age ≥75 years, diabetes mellitus, and prior stroke) to determine candidacy for anticoagulant prophylaxis in insured patients with atrial fibrillation (AF). M...
Source: Clinical Therapeutics - Category: Drugs & Pharmacology Authors: Tags: Clin Ther Source Type: research
Conclusion The trial focuses on a never previously studied high bleeding risk population characterized by advanced age and more comorbid conditions. It is the 1st evaluation of a DCS with clinical endpoints and comprises the shortest ever DAPT course with an active stent to be evaluated for both safety and efficacy.
Source: Archives of Cardiovascular Diseases Supplements - Category: Cardiology Source Type: research
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