Clinical and Laboratory Findings of MERS-CoV infection.

Clinical and Laboratory Findings of MERS-CoV infection. Jpn J Infect Dis. 2018 Dec 25;: Authors: Hwang SM, Na BJ, Jung YM, Lim HS, Seo JE, Park SN, Cho YS, Song EH, Seo JY, Kim SR, Lee GY, Kim SJ, Park YS, Seo HS Abstract There is a paucity of data regarding the differentiating characteristics of patients with laboratory confirmed and those negative for Middle East respiratory syndrome coronavirus (MERS-CoV) in South Korea. This is a hospital-based retrospective study comparing MERS-CoV-positive patients with MERS-CoV-negative patients. A total of 7 positive patients and 55 negative patients with a median age of 43 (P = 0.833) were included. No statistical differences were observed in relation to sex and the presence of comorbidities. At the time of admission, headache (28.6% vs 3.6%; OR, 10.60; 95% CI, 1.22-92.27), myalgia (57.1% vs. 9.1%; OR, 13.33; 95% CI, 2.30-77.24), and diarrhea (57.1% vs 14.5%; OR, 7.83; 95% CI, 1.47-41.79) were common among MERS-CoV-positive patients. MERS-CoV patients were more likely to have a low platelet count (164±76.57 vs 240±76.57) and eosinophil (0.27±0.43 vs. 2.13±2.01; p-value<0.001). Chest radiography with diffuse bronchopneumonia was more frequent in MERS-CoV-positive patients than in negative patients (100% vs 62.5%; p-value=0.491). Symptoms of headache, myalgia, and diarrhea, laboratory characteristics of low counts of platelet and eosinophil, Also, chest X-ray revealed that diffuse bronc...
Source: Japanese Journal of Infectious Diseases - Category: Infectious Diseases Authors: Tags: Jpn J Infect Dis Source Type: research