Cardiac surgery in infective endocarditis with neurological complications: Identifying prognosis risk factors in mortality and handicap at 6 months

Publication date: January 2019Source: Archives of Cardiovascular Diseases Supplements, Volume 11, Issue 1Author(s): G. Charbonnier, Y. Lavie-Badie, G. Robin, F. Labaste, D. Eyharts, P. Fournier, E. Cariou, L. Porte, B. Marcheix, J. Porterie, E. Grunenwald, C. Cron, M. Galinier, O. LairezBackgroundNeurological complications of infective endocarditis (IE) concerns 20–40% of cases when symptomatic and 70% when asymptomatic. It is a well-identified gravity factor. Surgical indications in IE are larges and usual in emergency situations. However, neurological event, symptomatic or not, counts in surgical discussion. Sub-groups of patients with real risk of neurological deterioration during extracorporeal circulation are difficult to identify. The purpose of this study was to identify the risk factors of death and handicap in patients operated for infective endocarditis with neurological complications.MethodsRetrospective monocentric study realized in CHU of Toulouse from October 2014 to March 2017. We included 78 patients treated by cardiac surgery in a context of infective endocarditis complicated by neurological event (ischemic or hemorrhagic stroke, meningitis or mycotic aneurysm). The primary endpoint was mortality and Rankins score greater than or equal to 2, at six month.ResultsPrimary endpoint occurred in 21 patients (26%). Risk factors were anteriority of mechanical valve replacement (P = 0,004), pejorative SOFA score (P 
Source: Archives of Cardiovascular Diseases Supplements - Category: Cardiology Source Type: research

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Source: Trends in Food Science and Technology - Category: Food Science Source Type: research
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Source: European Review for Medical and Pharmacological Sciences - Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
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Source: Journal of Maternal-Fetal and Neonatal Medicine - Category: Perinatology & Neonatology Authors: Source Type: research
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Source: Nitric Oxide - Category: Chemistry Source Type: research
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Source: Inorganica Chimica Acta - Category: Chemistry Source Type: research
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