Is there a difference in treatment outcome for monomicrobial and polymicrobial periprosthetic joint infections? Systematic review and study quality analysis

ConclusionsQuantitative analysis demonstrated that although polymicrobial infections have been identified as a risk factor for failure after a PJI, they did not result in significantly worse outcomes after treatment. Though not statistically significant, polymicrobial PJI with gram negative organisms typically resulted in poorer outcomes as compared to PJI with gram positive organisms. Antibiotic coverage should be evaluated to ensure proper coverage of such gram-negative organisms.Level of evidenceSystematic Review of Level III Studies.
Source: Journal of Arthroscopy and Joint Surgery - Category: Orthopaedics Source Type: research