Origin of the Y Chromosome Influences Intrarenal Vascular Responsiveness to Angiotensin I and Angiotensin (1-7) in Stroke-Prone Spontaneously Hypertensive Rats [Renin-Angiotensin System and Y Chromosome]

This study demonstrates that the origin of the Y chromosome significantly impacts the renal vascular responsiveness and therefore may influence the long-term renal regulation of blood pressure.

Source: Hypertension - November 12, 2014 Category: Cardiology Authors: Sampson, A. K., Andrews, K. L., Graham, D., McBride, M. W., Head, G. A., Thomas, M. C., Chin-Dusting, J. P. F., Dominiczak, A. F., Jennings, G. L. Tags: Cardio-renal physiology/pathophysiology, ACE/Angiotension receptors, Animal models of human disease, Other hypertension, Functional genomics, Genetics of cardiovascular disease Renin-Angiotensin System and Y Chromosome Source Type: research