ASCA (Anti-Saccharomyces cerevisiae Antibody) in Patients With Scleroderma

In this study we aimed to investigate ASCA positivity in SSc patients and its association with clinical, serological and epidemiological data. Methods Seventy-four SSc patients and 57 healthy controls were studied for ASCA (IgG and IgA) positivity by ELISA. ASCA positivity was associated with demographic, clinical severity index (by Medsger score) and serological data in SSc patients. Results ASCA-IgG was positive in 32/74 (43.2%) patients of the SSc group and 1/57 (1.7%) of controls (p
Source: JCR: Journal of Clinical Rheumatology - Category: Rheumatology Tags: Original Articles Source Type: research