Effect of disinfectant formulation and organic soil on the efficacy of oxidizing disinfectants against biofilms

This study compared the activity of formulated oxidizing disinfectants with products containing active ingredients against Staphylococcus aureus dry-surface biofilm (DSB) alone.MethodsDSB was grown in the CDC bioreactor with alternating cycles of hydration and dehydration. Disinfectant efficacy was tested before and after treatment with neutral detergent for 30 s, and in the presence or absence of standardized soil. Biofilms were treated for 5 min with peracetic acid (Surfex and Proxitane), hydrogen peroxide (Oxivir and 6% H2O2 solution) and chlorine (Chlorclean and sodium dichloroisocyanurate tablets). Residual biofilm viability and mass were determined by plate culture and protein assay, respectively.FindingsBiofilm viability was reduced by 2.8 log10 for the chlorine-based products and by 2 log10 for Proxitane, but these products failed to kill any biofilm in the presence of soil. In contrast, Surfex completely inactivated biofilm (6.3 log10 reduction in titre) in the presence of soil. H2O2 products had little effect against DSB. Biofilm mass removed in the presence and absence of soil was
Source: Journal of Hospital Infection - Category: Infectious Diseases Source Type: research

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In conclusion, the selected species from traditional products which presented a specific property may provide a wide range of genetic variants to design modified species with desired characteristics.
Source: LWT Food Science and Technology - Category: Food Science Source Type: research
Publication date: Available online 16 August 2019Source: Food ControlAuthor(s): María Isabel Rodríguez-López, María Teresa Mercader-Ros, José Antonio Pellicer, Vicente M. Gómez-López, Domingo Martínez-Romero, Estrella Núñez-Delicado, José A. GabaldónAbstractMonoterpenes have antimicrobial properties but are associated with strong smells and flavors that limit their use in foods; therefore, strategies to keep their effectivity using lower concentrations are required. This work tested the antimicrobial capacity of thymol, carvacrol and linalo...
Source: Food Control - Category: Food Science Source Type: research
Publication date: Available online 19 August 2019Source: Microbial PathogenesisAuthor(s): Baifen Song, Jianxin Zhang, Jinzhu Ma, Zhenyue Feng, Liquan Yu, Yongzhong Yu, Yudong CuiAbstractThe purpose of this investigation was to construct a recombinant Escherichia coli strain displaying the Staphylococcus aureus target of RNAIII activating protein (TRAP) on its surface, and to investigate the strain for its immunogenicity. The lpp'ompA and lpp'ompA-TRAP genes were fused by the overlap polymerase chain reaction and then ligated into expression plasmid pQE30 producing pLO and pLO-TRAP. These two recombinant plasmids were trans...
Source: Microbial Pathogenesis - Category: Infectious Diseases Source Type: research
Source: Infection and Drug Resistance - Category: Infectious Diseases Tags: Infection and Drug Resistance Source Type: research
Publication date: Available online 17 August 2019Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Alexandra Leonard, Jingya Wang, Li Yu, Hao Liu, Yeriel Estrada, Lydia Greenlees, Roderick McPhee, Alexey Ruzin, Emma Guttman-Yassky, Michael D. HowellAbstractBackgroundAtopic dermatitis (AD) is a chronic inflammatory disease with significant local and systemic inflammation and barrier disruption. AD is associated with increased risk of allergen sensitization and skin colonization by Staphylococcus aureus. The heterogeneity of AD is unknown, and its complexity suggests its subdivision into several e...
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research
Microbial Drug Resistance, Ahead of Print.
Source: Microbial Drug Resistance - Category: Microbiology Authors: Source Type: research
Microbial Drug Resistance, Ahead of Print.
Source: Microbial Drug Resistance - Category: Microbiology Authors: Source Type: research
Publication date: January 2020Source: Food Control, Volume 107Author(s): Angelo Colagiorgi, Rossella Festa, Pierluigi A. Di Ciccio, Marta Gogliettino, Marco Balestrieri, Gianna Palmieri, Aniello Anastasio, Adriana IanieriAbstractStaphylococcal food poisoning – caused by certain enterotoxigenic staphylococci – is one of the most common worldwide foodborne diseases. In this context, bacterial biofilms on food processing plan surfaces can represent critical sources of contamination, being more resistant to cleaning and disinfection procedures. Therefore, it is important to prevent and control biofilm formation in ...
Source: Food Control - Category: Food Science Source Type: research
Halogenated boroxine dipotassium trioxohydroxytetrafluorotriborate K2[B3O3F4OH] inhibits emerging multidrug-resistant and β-lactamase-producing opportunistic pathogens. Drug Dev Ind Pharm. 2019 Aug 16;:1-21 Authors: Maravić A, Rončević T, Krce L, Ilić N, Galić B, Čikeš Čulić V, Carev I Abstract Halogenated boroxine dipotassium trioxohydroxytetrafluorotriborate, K2[B3O3F4OH] (boroxine) was previously shown to be very effective in inhibition of several carcinoma cell lines, including the skin cancer. Here, we investigated its antimicrobial potential by targeting the multidrug-resistan...
Source: Drug Development and Industrial Pharmacy - Category: Drugs & Pharmacology Tags: Drug Dev Ind Pharm Source Type: research
Authors: Zheng S PMID: 31416994 [PubMed - in process]
Source: Hong Kong Medical Journal - Category: General Medicine Tags: Hong Kong Med J Source Type: research
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