Automatically configuring the reference point method for automated multi-objective treatment planning.

Automatically configuring the reference point method for automated multi-objective treatment planning. Phys Med Biol. 2018 Dec 19;: Authors: van Haveren R, Heijmen BJM, Breedveld S Abstract Automated treatment planning algorithms have demonstrated capability in generating consistent and high quality treatment plans. Their configuration (i.e. determining the algorithm's parameters), however, can be a labour-intensive and time-consuming trial-and-error procedure. 
 
 Previously, we introduced the reference point method (RPM) for fast automated multi-objective treatment planning. The RPM generates a single Pareto optimal plan for each patient. When the RPM is configured appropriately, this plan has clinically favourable trade-offs between all plan objectives. This paper proposes a new procedure to automatically generate a single configuration of the RPM per tumour site. The procedure was tested for prostate cancer.
 
 Planning CT scans of 287 previously treated patients were included in a database, together with corresponding Pareto optimal plans generated using our clinically applied 2-phase ԑ-constraint method (part of Erasmus-iCycle) for automated multi-objective treatment planning. The procedure developed acquires plan characteristics observed in a training set. Based on these, an RPM configuration is automatically generated according to user preferences which specify acceptable differences between t...
Source: Physics in Medicine and Biology - Category: Physics Authors: Tags: Phys Med Biol Source Type: research