Immediate-hypersensitivity reactions to proton pump inhibitors

Proton pump inhibitors (PPIs) are prescribed worldwide for the treatment of acid-peptic diseases.1 –3 They antagonize the enzyme H+/K+ adenosine triphosphatase in gastric cells, inhibiting acid secretion and raising gastric pH.3,4 Side effects related to PPIs are reported in only 1% to 3% of treated patients.1,5 Omeprazole, esomeprazole, and pantoprazole have a similar chemical structure, diffe ring from rabeprazole and lansoprazole.1,5
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: Letter Source Type: research