Associations of postmenopausal hormone therapy with metabolic syndrome among diabetic and non-diabetic women

With the rising prevalence of metabolic syndrome (MetS), diabetes and mortality from cardiovascular disease (CVD) have also increased [1 –3]. As people age, sex differences in the prevalence of MetS and each of its component are observed [4]. Furthermore, women after menopause have a higher prevalence of MetS compared with premenopausal women regardless of age [5]. This phenomenon is related to estrogen deficiency caused by menopau se. Thus, the alteration of metabolic homeostasis via estrogen deficiency predisposes many women to MetS [6].
Source: Maturitas - Category: Primary Care Authors: Source Type: research

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Publication date: Available online 13 July 2019Source: Diabetes &Metabolic Syndrome: Clinical Research &ReviewsAuthor(s): Naser Parizad, Vajiheh Baghi, Elnaz Baghban Karimi, Reza Ghanei GheshlaghAbstractOsteoporosis is the most common metabolic bone disorder that is common in postmenopausal women with type 2 diabetes. Different studies have reported different prevalence of osteoporosis. This systematic review and meta-analysis was conducted to estimate the pooled prevalence of osteoporosis in Iranian postmenopausal women with type 2 diabetes. Search for eligible articles was performed using the keywords of osteopor...
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - Category: Endocrinology Source Type: research
ConclusionDYP reduced the HbA1C and stress levels and therefore, could be a cost-effective tool for preventing Prediabetic to Diabetic progression.
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - Category: Endocrinology Source Type: research
CONCLUSIONS: Insufficient riboflavin intake may contribute to development of cardiometabolic disorder, particularly in women. It was also found that riboflavin may have different influences on its risks in women according to menopausal status. This study highlighted the importance of public policies targeted at these sex-specific groups for reducing cardiometabolic risks. PMID: 31192558 [PubMed - in process]
Source: Asia Pacific Journal of Clinical Nutrition - Category: Nutrition Authors: Tags: Asia Pac J Clin Nutr Source Type: research
(The North American Menopause Society (NAMS)) Vitamin D and estrogen have already shown well-documented results in improving bone health in women. A new study from China suggests that this same combination could help prevent metabolic syndrome, a constellation of conditions that increases the risk of heart disease, stroke, and diabetes in postmenopausal women. Results are published online today in Menopause, the journal of The North American Menopause Society (NAMS).
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
DiscussionThe findings of this study suggest that the GG genotype of SNP (rs556442) could protective role in obese women through the association with BMR.
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - Category: Endocrinology Source Type: research
Menopause is associated with an increasing risk to develop the so called metabolic syndrome. A major reason is the decrease of circulating estrogen, a sex steroid which is involved in a variety of metabolic processes. Estrogens affect fat metabolism, bone metabolism and protein metabolism. Declining estrogen levels are associated with adverse lipid profiles, a reduced ability o to metabolize fatty acids, reduced bone mass and density and with a decrease in skeletal muscle mass. All this has implications for the development of diseases like cardiovascular disease, sarcopenia, osteoporosis and diabetes type II.
Source: Maturitas - Category: Primary Care Authors: Tags: INV10 Source Type: research
Publication date: Available online 4 May 2019Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): P. Sankar, P. Rajaa Muthu, Zachariah Bobby, M.G. SridharAbstractPostmenopausal women are more prone to develop metabolic syndrome (MetS) components; insulin resistance, type2 diabetes, dyslipidemia, atherosclerosis and obesity than premenopausal women. Oxidative stress (OxS) and inflammation (INF) are emerged as major triggers for these metabolic consequences. However, the pathogenesis of OxS and inflammation after menopause is only partially understood which is yet to be elucidated. The lack of safe/effective c...
Source: Nutrition, Metabolism and Cardiovascular Diseases - Category: Nutrition Source Type: research
Filomena Corbo1†, Giacomina Brunetti2*†, Pasquale Crupi3, Sara Bortolotti4, Giuseppina Storlino4, Laura Piacente5, Alessia Carocci1, Alessia Catalano1, Gualtiero Milani1, Graziana Colaianni4, Silvia Colucci2, Maria Grano4, Carlo Franchini1, Maria Lisa Clodoveo6, Gabriele D'Amato7 and Maria Felicia Faienza5 1Department of Pharmacy-Drug science, University of Bari Aldo Moro, Bari, Italy 2Section of Human Anatomy and Histology, Department of Basic and Medical Sciences, Neurosciences and Sense Organs, University of Bari Aldo Moro, Bari, Italy 3CREA-VE, Council for Agricultural Research and Economics&ndas...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
We examined the effects of the independent and combined effects of Zataria Multiflora supplementation and circuit resistance training (CRT) on selected adipokines among postmenopausal women. Forty-eight postmenopausal women were divided into four groups: Exercise (EG, n = 12), Zataria Multiflora (ZMG, n = 12), exercise and Zataria Multiflora (ZMEG, n = 12), and control (CG, n = 12). Participants in experimental groups either performed CRT (3 sessions per week with intensity at 55% of one-repetition maximum) or supplemented with Zataria Multiflora (500 mg every day after breakfast with 100 ml of water), or their combination...
Source: Frontiers in Physiology - Category: Physiology Source Type: research
Conclusions The concept of osteoimmunology is aging well, almost 20 years since the term was coined. This way of interpreting bone and the immune system has been steadily providing new insights about how the two of them operate and cooperate. As an example, the role of pro-inflammatory cytokines in promoting osteoclastogenesis, and the many parallelisms between immune cells and osteoclasts have proved crucial to understand the biology of these giant bone-eating cells. Intriguingly, the control mechanisms between bone and the immune system are complex, tightly interconnected, and involve many players. The underlying comple...
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
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