Chronic Urticaria and Osteoporosis: A longitudinal, Community-based Cohort Study of 11,944 Patients.

Chronic Urticaria and Osteoporosis: A longitudinal, Community-based Cohort Study of 11,944 Patients. Br J Dermatol. 2018 Dec 18;: Authors: Shalom G, Kridin K, Babaev M, Magen E, Tiosano S, Dreiher J, Horev A, Khury R, Comaneshter D, Agmon-Levin N, Cohen AD Abstract BACKGROUND: Chronic urticaria (CU) carries many risk factors for osteoporosis, but data on the relation between CU and osteoporosis are lacking. OBJECTIVE: To evaluate the association between CU and osteoporosis in a large community-based study. METHODS: A nationwide observational longitudinal cohort study was conducted. CU was defined as four couples with urticaria diagnoses; each couple was recorded within a period of six weeks and was registered by physicians in a primary care setting. CU patients and their age- and gender- matched controls were followed for the incidence of osteoporosis and other laboratory data between 2002-2017. Data regarding systemic steroids exposure and other relevant risk factors for osteoporosis were obtained. Analyses of risk for osteoporosis were performed in Cox regression models adjusted for age, sex, exposure to systemic corticosteroids, obesity, smoking, hyper- and hypo- thyroid disease. RESULTS: The study included 11,944 patients with CU and 59,829 controls. During the study's observation period 1,035 (8.7%) patients with CU were diagnosed with osteoporosis compared with 4,046 (6.8%) controls. The adjusted multivariate analysis demonstrated th...
Source: The British Journal of Dermatology - Category: Dermatology Authors: Tags: Br J Dermatol Source Type: research

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Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
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Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
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Source: Revista da Escola de Enfermagem da USP - Category: Nursing Source Type: research
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Source: Diabetologia - Category: Endocrinology Source Type: research
AbstractAims/hypothesisThe aim of this study was to investigate the concordance of dysglycaemia (prediabetes or diabetes) and cardiometabolic traits between women with a history of gestational diabetes mellitus (GDM) and their spouses.MethodsUsing hospital medical records, women with GDM (diagnosed between 2012 and 2016) and their spouses were invited to participate in the study and to attend a scheduled hospital visit in a fasting state. Sociodemographic, anthropometric and medical data were collected, and a 75  g OGTT with serum insulin estimation, HbA1c measurement and fasting lipid profile were performed at the vi...
Source: Diabetologia - Category: Endocrinology Source Type: research
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Source: Diabetologia - Category: Endocrinology Source Type: research
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Source: Diabetologia - Category: Endocrinology Source Type: research
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Source: the Mail online | Health - Category: Consumer Health News Source Type: news
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Source: Pharmacological Research - Category: Drugs & Pharmacology Source Type: research
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