Safety of Electromagnetic Navigation Bronchoscopy in Patients With COPD: Results From the NAVIGATE Study

Conclusion: In this analysis, complication rates following ENB procedures were not increased in patients with COPD or poor pulmonary function. Because pneumothorax risk is not elevated, ENB may be the preferred method to biopsy peripheral lung lesions in patients with COPD and/or poor pulmonary function testing.
Source: Journal of Bronchology and Interventional Pulmonology - Category: Respiratory Medicine Tags: Original Investigations Source Type: research

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Authors: Sánchez-Villegas P, Cabrera-León A, Gil García E Abstract OBJECTIVE: To describe the association between the Neighborhood Walkability and mortality. METHOD: Ecological study of small areas. The standardized mortality ratios (SMR) and the Walk Score© were calculated in each census tract. These values were compared with parametric and nonparametric tests. RESULTS: For men, in the case of ischemic diseases, the means of the SMR for the categories with the highest walkability and the least were 1.03 and 0.85 (p
Source: Gaceta Sanitaria - Category: International Medicine & Public Health Tags: Gac Sanit Source Type: research
CONCLUSION: CE modulates cortisol, testosterone, and immunoglobulin A levels without the change in immunological parameters in ILWHA. PMID: 31527301 [PubMed - as supplied by publisher]
Source: Journal of Physical Activity and Health - Category: Sports Medicine Tags: J Phys Act Health Source Type: research
Erratum - Salonen PH, Säilä H, Salonen JH, Linna M, Helminen M, Kauppi MJ: Pneumonia in children with juvenile idiopathic arthritis in Finland 1999-2014: a nationwide retrospective register linkage study". Clin Exp Rheumatol 2018; 36: 502-7. Clin Exp Rheumatol. 2019 Sep-Oct;37(5):888 Authors: Salonen PH, Säilä H, Salonen JH, Linna M, Helminen M, Kauppi MJ PMID: 31530347 [PubMed]
Source: Clinical and Experimental Rheumatology - Category: Rheumatology Tags: Clin Exp Rheumatol Source Type: research
This study seeks to evaluate the use of CR in children with bronchiolitis due to a lower respiratory tract infection (RSV-RTI) with respiratory syncytial virus (RSV) and the influence of CR on patient treatment during the 2010-2017 seasons. There were 581 children included into the study: 459 with bronchiolitis (390 RSV-RTI and 69 non-RSV), 65 with RSV pneumonia and 57 with RSV bronchitis. We found that CR was performed in 28.6% (166/581) patients. CR was much more frequent in patients with RSV than non-RSV infections (61% vs. 31%). CR prognostic sensitivity and specificity in guiding antibiotic treatment was low, 78% and ...
Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research
The implementation of test-and-treat policies that recommend early initiation of ART may help curb the spread of HIV.HIV Medicine
Source: Medscape Hiv-Aids Headlines - Category: Infectious Diseases Tags: HIV/AIDS Journal Article Source Type: news
CONCLUSIONS: Although ART scale-up was temporally associated with a decline in TB notification rates, the achieved rates of decline are below those required to achieve the End TB Targets. Additional investments in tuberculosis control should include efforts to promote earlier care seeking and ART initiation among HIV-positive persons. PMID: 31529618 [PubMed - in process]
Source: Journal of the International AIDS Society - Category: Infectious Diseases Tags: J Int AIDS Soc Source Type: research
CONCLUSIONS: A formalized step-wise approach to including pregnant women in antiretroviral drug research should become the new norm. Systematic implementation of this approach would yield more timely and higher quality pregnancy dosing, safety and efficacy data. Through more vigorous action, regulatory bodies could responsibly overcome reluctance to include pregnant women in drug trials. Funders, researchers and programme implementers need to be galvanized to progressively include pregnant women in research - the use of newer, more effective drugs in women is at stake (349). PMID: 31529598 [PubMed - in process]
Source: Journal of the International AIDS Society - Category: Infectious Diseases Tags: J Int AIDS Soc Source Type: research
ConclusionThe widespread availability and recommendation of synthetic compounds for addressing human health have several side effects besides higher costs. Hence, examining natural bioactive compounds is imperative. This review investigates and presents the pertinent information on cardamom and its traditional uses, as well as potential pharmacological properties of CEO and extracts. Additional research studies are needed to understand the mechanism of action of bioactive constituents.Graphical abstract
Source: Journal of Ethnopharmacology - Category: Drugs & Pharmacology Source Type: research
Contributors : Sandra Ruiz-Garcia ; Marie Deprez ; K Lebrigand ; A Paquet ; A Cavard ; I Caballero ; M J Arguel ; S Leroy ; C H Marquette ; P Barbry ; L E ZaragosiSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiens ; Mus musculus ; Sus scrofaThe upper airway epithelium is mainly composed of 4 cell types: multiciliated, goblet, secretory and basal cells. It constitutes an efficient first line of defense of the respiratory tract against a large panel of inhaled substances. Upon injury, regeneration of this epithelium through proliferation and differentiation events can restore a proper muc...
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Mus musculus Sus scrofa Source Type: research
Publication date: Available online 18 September 2019Source: Journal of Clinical NeuroscienceAuthor(s): Yahia Zaid, Abbas Rajeh, Saeed Hosseini Teshnizi, Ali Alqarn, Firoozeh Tarkesh, Zahra Esmaeilinezhad, Reza NikandishAbstractBackground/objectiveStroke is the second leading cause of death globally that predisposed to sepsis. Therefore, this study was aimed to assess the risk factors and epidemiologic features of sepsis in ischemic stroke patients admitted to ICUs.MethodsThroughout this prospective study, we investigated all severe ischemic stroke patients admitted to ICUs of Namazi and Ali-Ashghar Hospitals in Shiraz. Aft...
Source: Journal of Clinical Neuroscience - Category: Neuroscience Source Type: research
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