Vascular and metabolic profiles in offspring born to  pregnant mice with metabolic syndrome treated with inositols

Inositols (INOs) supplementation during pregnancy, specifically the combination of myo-inositol (MI) and D-chiro-inositol (DCI), has been reported to improve vascular parameters in women with gestational diabetes mellitus. We demonstrated previously that offspring born to pregnant mice lacking the endothelial nitric oxide synthase (eNOS+/ –) gene have hypertension (HTN) as adults and, when fed a high-fat diet (HFD), develop a metabolic syndrome (MS) phenotype.
Source: American Journal of Obstetrics and Gynecology - Category: OBGYN Authors: Tags: Original Research Source Type: research