Blood endotyping distinguishes the profile of vitiligo from other inflammatory and autoimmune skin diseases

Vitiligo is distinguished from other inflammatory skin diseases by strong Th1 polarization, along with elevated Th2/Th9/Th17/Th22 and low Treg frequency in blood. Future targeted therapeutic studies are needed to define the relative contribution of each skewed cytokine axis.

Source: Journal of Allergy and Clinical Immunology - December 18, 2018 Category: Allergy & Immunology Authors: Tali Czarnowicki, Helen Y. He, Alexandra Leonard, Hyun Je Kim, Naoya Kameyama, Ana B. Pavel, Randall Li, Yeriel Estrada, Huei-Chi Wen, Grace W. Kimmel, Hee J. Kim, Margot Chima, Mark Lebwohl, James G. Krueger, Emma Guttman-Yassky Source Type: research