Medical News Today: What are the health benefits of 5-HTP?

L-5 hydroxytryptophan (5-HTP) is a naturally occurring compound in the body. It is related to the production of serotonin, so some people think that it may aid weight loss, treat sleep problems, and help manage depression. Learn more about 5-HTP supplements in this article.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Mental Health Source Type: news

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AbstractPurpose of ReviewIn this review, we aim to integrate the most recent research highlighting alterations in sleep slow-wave activity (SWA), and impairments in neuroplasticity in major depressive disorder (MDD) into a novel model of disorder maintenance.Recent FindingsSleep homeostasis has been shown to be impaired in MDD, with a subset of individuals also demonstrating impaired SWA. SWA is considered a marker of the homeostatic regulation of sleep, and is implicated in the downscaling of synaptic strength in the context of maintaining homeostatic plasticity. Individuals with MDD have been shown to exhibit impairments...
Source: Current Psychiatry Reports - Category: Psychiatry Source Type: research
Authors: Malegiannaki AC, Katsarou D, Liolios A, Zisi V Abstract Individuals with Down Syndrome (DS) are commonly characterized by unique neurocognitive and neurobehavioural profiles that emerge within specific stages in the developmental continuum. A plethora of studies have confirmed DS's relationship to premature aging and subsequent cognitive decline. Due to having three copies of the amyloid precursor protein (APP) gene which results in amyloid-beta plaque deposition, the cognitive decline often resembles the decline observed in Alzheimer's disease. More specifically, as individuals with DS mature in age (>...
Source: Hellenic Journal of Nuclear Medicine - Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research
Publication date: Available online 14 March 2019Source: Journal of Acupuncture and Meridian StudiesAuthor(s): Yun Jin KimAbstractSleep disturbance is one of the most common risk factors and symptoms of other negative physical health outcomes, and it is defined as self-reported poor quality of sleep, short sleep duration, daytime sleepiness, and insomnia symptoms. It is a common risk factor for depression and anxiety. Here, a case of sleep disturbance that received 72 sessions of acupuncture treatment delivered is reported. After acupuncture treatment, the patient's Pittsburgh Sleep Quality Index, Hamilton Depression R...
Source: Journal of Acupuncture and Meridian Studies - Category: Complementary Medicine Source Type: research
Publication date: Available online 15 March 2019Source: Journal of Psychiatric ResearchAuthor(s): Markus Gerber, Alice Minghetti, Johannes Beck, Lukas Zahner, Lars DonathAbstractMajor depressive disorder (MDD) is one of the most burdensome disorders worldwide. While exercise training in patients with MDD contributes to clinically relevant improvements in cardiorespiratory fitness, whether and to what degree changes in cardiorespiratory fitness impact depressive symptom severity has not yet been addressed systematically in prior research. The purpose of our study was threefold. Firstly, to examine whether baseline levels an...
Source: Journal of Psychiatric Research - Category: Psychiatry Source Type: research
Publication date: Available online 14 March 2019Source: Journal of Acupuncture and Meridian StudiesAuthor(s): Yun Jin KimAbstractSleep disturbance is one of the more common risk factors, numerous other negative physical health outcomes, and it is defined as self-reported poor quality of sleep, short sleep duration, daytime sleepiness, and insomnia symptoms. It is a common risk factor for depression and anxiety. Here, a case of sleep disturbance that received 72 sessions of acupuncture treatment delivered is reported. After acupuncture treatment, the patient’s PSQI, HDRS, and SAS score decreased, as well as the plasma...
Source: Journal of Acupuncture and Meridian Studies - Category: Complementary Medicine Source Type: research
Publication date: Available online 14 March 2019Source: The Lancet PsychiatryAuthor(s): Becky Mars, Jon Heron, E David Klonsky, Paul Moran, Rory C O'Connor, Kate Tilling, Paul Wilkinson, David GunnellSummaryBackgroundSuicidal thoughts and non-suicidal self-harm are common in adolescents and are strongly associated with suicide attempts. We aimed to identify predictors of future suicide attempts in these high-risk groups.MethodsParticipants were from the Avon Longitudinal Study of Parents and Children, a population-based birth cohort study in the UK. The sample included 456 adolescents who reported suicidal thoughts and 569...
Source: The Lancet Psychiatry - Category: Psychiatry Source Type: research
Source: Journal of Clinical Sleep Medicine : JCSM - Category: Sleep Medicine Source Type: research
CONCLUSIONS: Patients prescribed oral therapies struggle with adherence, and cancer-related symptom burden is high and related to worse adherence and QoL. Given perceptions that oral therapies are less impairing, these data underscore the strong need to address adherence issues, symptom burden, and QoL for these patients. PMID: 30865917 [PubMed - in process]
Source: Journal of the National Comprehensive Cancer Network : JNCCN - Category: Cancer & Oncology Tags: J Natl Compr Canc Netw Source Type: research
This study investigated the extent to which state and trait anxiety predicted self-reported sleep difficulties in healthy older adults. We present an analysis of the baseline data (n = 292) collected as part of the Australian Research Council Longevity Intervention (ARCLI) study. Participants were aged between 60 and 75 years (M = 65.88, SD = 4.01). Sleep difficulties were assessed using a modified version of the Leeds Sleep Evaluation Questionnaire and state/trait anxiety was assessed using the Spielberger State-Trait Anxiety Inventory. Regression was used to examine the association between state anxiety and...
Source: Personality and Individual Differences - Category: Psychiatry & Psychology Source Type: research
Conclusions: Aging increased the SCD risk. People with SCD had suboptimal performance in mental health and life quality in addition to subjective cognition problems.Dement Geriatr Cogn Disord Extra 2019;9:152 –162
Source: Dementia and Geriatric Cognitive Disorders Extra - Category: Geriatrics Source Type: research
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