Iron-related nigral degeneration influences functional topology mediated by striatal dysfunction in Parkinson's disease.

In conclusion, our findings reveal that iron-related nigral degeneration possibly influences the functional topology mediated by striatal dysfunction, which extends the scientific understanding of PD pathogenesis.
PMID: 30554085 [PubMed - as supplied by publisher]

Source: Neurobiology of Aging - November 22, 2018 Category: Geriatrics Authors: Guan X, Zhang Y, Wei H, Guo T, Zeng Q, Zhou C, Wang J, Gao T, Xuan M, Gu Q, Xu X, Huang P, Pu J, Zhang B, Liu C, Zhang M Tags: Neurobiol Aging Source Type: research