The effect of a mixture of 2.7% sorbitol-0.54% mannitol solution on blood coagulation: an in-vitro, observational healthy-volunteer study using rotational thromboelastometry (ROTEM).

Conclusion: Blood became hypocoagulable when it was diluted in vitro with a mixture of 2.7% sorbitol-0.54% mannitol solution. Clot stabilization with fibrin polymerization seemed to be disturbed primarily rather than the initiation of clotting in coagulation pathway. PMID: 30553238 [PubMed - as supplied by publisher]
Source: Korean Journal of Anesthesiology - Category: Anesthesiology Tags: Korean J Anesthesiol Source Type: research