Development of a High-Resolution Melting Curve Analysis Screening Test for Splicing Factor Gene Mutations in Myelodysplastic Syndromes

We describe a high-resolution melting (HRM) curve analysis to screen for SRSF2 hotspot mutations in a fast, sensitive, and reliable way.

Source: Journal of Molecular Diagnostics - October 24, 2014 Category: Pathology Authors: Eduardo Garza, Emiliano Fabiani, Nelida Noguera, Paola Panetta, Maria Liliana Piredda, Loredana Borgia, Luca Maurillo, Gianfranco Catalano, Maria Teresa Voso, Francesco Lo-Coco Tags: Regular Article Source Type: research