Runaway Immune System May Play Role in Chronic Fatigue Syndrome

MONDAY, Dec. 17, 2018 -- Researchers say they've pinpointed a possible culprit in chronic fatigue syndrome (CFS), reporting that an overactive immune system might send the entire body into an overwhelming state of exhaustion. " For the first time,...
Source: Drugs.com - Daily MedNews - Category: General Medicine Source Type: news

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im Saurabh Chatterjee Gulf War illness (GWI) is characterized by the persistence of inflammatory bowel disease, chronic fatigue, neuroinflammation, headache, cognitive impairment, and other medically unexplained conditions. Results using a murine model show that enteric viral populations especially bacteriophages were altered in GWI. The increased viral richness and alpha diversity correlated positively with gut bacterial dysbiosis and proinflammatory cytokines. Altered virome signature in GWI mice also had a concomitant weakening of intestinal epithelial tight junctions with a significant increase in Claudin-2 prote...
Source: Viruses - Category: Virology Authors: Tags: Article Source Type: research
Publication date: 19 October 2019Source: New Scientist, Volume 244, Issue 3252Author(s): Clare Wilson
Source: New Scientist - Category: Science Source Type: research
Publication date: Available online 19 October 2019Source: NeuroImage: ClinicalAuthor(s): Leighton R Barnden, Zack Y Shan, Donald R Staines, Sonya Marshall-Gradisnik, Kevin Finegan, Timothy Ireland, Sandeep BhutaAbstractIn myalgic encephalomyelitis or chronic fatigue syndrome (ME/CFS), abnormal MRI correlations with symptom severity and autonomic measures have suggested impaired nerve signal conduction within the brainstem. Here we analyse fMRI correlations to directly test connectivity within and from the brainstem. Resting and task functional MRI (fMRI) were acquired for 45 ME/CFS (Fukuda criteria) and 27 healthy controls...
Source: NeuroImage: Clinical - Category: Radiology Source Type: research
Authors: Maes M, Rodriguez LA, Morris G PMID: 31617771 [PubMed - as supplied by publisher]
Source: Expert Review of Molecular Diagnostics - Category: Laboratory Medicine Tags: Expert Rev Mol Diagn Source Type: research
Publication date: 2019Source: International Review of Neurobiology, Volume 147Author(s): Jessie S.M. Chan, Siu-Man Ng, Lai-Ping Yuen, Cecilia L.W. ChanAbstractChronic fatigue syndrome (CFS) is often overlooked, has unclear etiology and no effective cure except some symptomatic treatments. Additionally, most people with CFS do not seek medical attention. Qigong exercise, an ancient Eastern body-mind-spirit practice, has been long practiced in Chinese communities and may powerfully trigger the self-healing process. Using full baseline data (n = 1409), the average Hong Kong CFS respondent was found to be female, mar...
Source: International Review of Neurobiology - Category: Neuroscience Source Type: research
Most people who think they have chronic Lyme disease are more likely to have chronic fatigue syndrome, say experts.
Source: BBC News | Health | UK Edition - Category: Consumer Health News Source Type: news
People who think they have a long-lasting form of Lyme disease are taking antibiotics for many months and may be treating the wrong disease
Source: New Scientist - Health - Category: Consumer Health News Source Type: research
CONCLUSIONS: Exercise therapy probably has a positive effect on fatigue in adults with CFS compared to usual care or passive therapies. The evidence regarding adverse effects is uncertain. Due to limited evidence it is difficult to draw conclusions about the comparative effectiveness of CBT, adaptive pacing or other interventions. All studies were conducted with outpatients diagnosed with 1994 criteria of the Centers for Disease Control and Prevention or the Oxford criteria, or both. Patients diagnosed using other criteria may experience different effects. PMID: 31577366 [PubMed - as supplied by publisher]
Source: Cochrane Database of Systematic Reviews - Category: General Medicine Authors: Tags: Cochrane Database Syst Rev Source Type: research
Date: Tuesday, 10 01, 2019; Speaker: Drs. Panos Kassavetis&Patrick Bedard, NINDS; Dr. Brian Walitt, NINR; Building: Building 10 (Clinical Center); Lipsett Auditorium; CME Credit
Source: NIH Calendar of Events - Category: American Health Source Type: events
Today, Cochrane publishes an amended version of the Review,' Exercise therapy for chronic fatigue syndrome. ’ In the last nine months, this Cochrane Review has been modified by the review ’s authors and evaluated by independent peer reviewers and editors. It now places more emphasis on the limited applicability of the evidence to definitions of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) used in the included studies, the long-term effects of exercise on symptoms of fatigue, and acknowledges the limitations of the evidence about harms that may occur.Cochrane ’s Editor-in-Chief, Dr Karla Soa...
Source: Cochrane News and Events - Category: Information Technology Authors: Source Type: news
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