Axillary Pathologic Complete Response to Neoadjuvant Chemotherapy in Clinically Node-Positive Breast Cancer Patients: A Predictive Model Integrating the Imaging Characteristics of Ultrasound Restaging with Known Clinicopathologic Characteristics

The goal of this study was to evaluate various clinicopathologic and imaging characteristics as independent predictors of axillary pathologic complete response (pCR) to neoadjuvant chemotherapy (NAC) and to determine the added value of a model that integrates imaging characteristics of ultrasound (US) restaging with known clinicopathologic characteristics. A total of 227 clinically node-positive breast cancer patients underwent axillary US after NAC (termed US restaging) before surgery. We constructed a clinicopathologic model with independent predictors of clinicopathologic characteristics in multivariate analyses.

Source: Ultrasound in Medicine and Biology - December 17, 2018 Category: Radiology Authors: Won Hwa Kim, Hye Jung Kim, Ho Yong Park, Ji Young Park, Yee Soo Chae, So Mi Lee, Seung Hyun Cho, Kyung Min Shin, Sang Yub Lee Tags: Original Contribution Source Type: research