Research and Reviews in the Fastlane 057

This study compared bivalirudin to unfractionated heparin with the primary combined endpoint of death, CVA, reinfarction and target lesion revascularization. In spite of the fact that the trial was designed to favor bivalirudin (open-label), the authors found an increased rate in the primary outcome in the bivalirudin group (8.7% vs. 5.7%). Further proof that just because a drug is new, doesn’t mean it’s better. Recommended by: Anand Swaminathan Trauma, PediatricsAltgärde J, Redéen S, Hilding N, Drott P. Horse-related trauma in children and adults during a two year period. Scand J Trauma Resusc Emerg Med. 2014 Jul 17;22(1):40. PMID 25030979 A colleague of mine once said “never ride an 500 kg animal with a brain the size of a walnut”. In this 2-year review of horse related injuries in a Swedish University Hospital. To no surprise most injuries were orthopedic and minor, but among 188 patients (147 children), 19 were considered having a serious injury, four patients needed treatment in intensive care units, none died. Recommended by: Søren Rudolph Emergency medicine     Malo C et al. Tamsulosin for treatment of unilateral distal ureterolithiasis: a systematic review and metaanalysis. CJEM 2013; 15(0):1-14 PMID 23870675 This study is a meta-analysis looking at whether tamsulosin increases the rate of spontaneous stone passage in patients with renal colic. The authors report a benefit to the drug with a RR for passage of 1.50. However,...
Source: Life in the Fast Lane - Category: Emergency Medicine Authors: Tags: Cardiology Education Emergency Medicine Pediatrics Resuscitation Trauma Wilderness Medicine airway brain failure critical care General Surgery hypothermia Intensive Care prehospital recommendations Review Source Type: blogs