Comparison of a twice-daily injection of insulin aspart 50 with insulin aspart 30 in patients with poorly controlled type 2 diabetes.

CONCLUSIONS: Compared with BIAsp30, BIAsp50 showed greater efficacy in patients with baseline BG excursion>7.8 mmol/L or 2hPBG>17.6 mmol/L as well as good safety for hypoglycaemia. CLINICAL TRIAL REGISTRATION: ChiCTR-IIR-16008958. PMID: 30550344 [PubMed - as supplied by publisher]
Source: Current Medical Research and Opinion - Category: Research Tags: Curr Med Res Opin Source Type: research

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CONCLUSION: The genotypic distribution of Chr-11 tRNA-Lys-CUU in our population was consistent to that reported by others. This gene failed as a marker for T2DM predisposition. PMID: 30882233 [PubMed - as supplied by publisher]
Source: Future Medicine: Biomarkers in Medicine - Category: Internal Medicine Tags: Biomark Med Source Type: research
Jianping Chen, Lin Zheng, Zhaoliu Hu, Fochang Wang, Shiying Huang, Zhonggui Li, Ping Zheng, Shangbin Zhang, Tiegang Yi, Huilin Li
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
ConclusionThe literature reports lower concentrations of systemic sTWEAK in T2DM which may be comparable to our observations in CP + T2DM when compared to health and its negative correlation with all the parameters suggesting an association with both clinical periodontal parameters and glycemic levels. However, serum sTWEAK levels may not be necessarily elevated in periodontitis as previously reported, and hence has the potential to be studied extensively for clarification with its association with T2DM.
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - Category: Endocrinology Source Type: research
Resumo Investigar os fatores associados ao controle glic êmico de pessoas com diabetes mellitus (DM). Estudo transversal realizado com 746 pessoas com DM tipo 2 e 40 anos ou mais de idade. Elegeu-se as seguintes variáveis: socioeconômicas, dados clínicos, estilo de vida e o risco para o desenvolvimento de úlceras nos pés. A coleta dos dados ocorreu por meio de entrevista, análise do prontuário e exame clínico dos membros inferiores. Utilizou-se o modelo de regressão múltipla de Poisson para determinação das razões de preval&ecir...
Source: Ciencia e Saude Coletiva - Category: Occupational Health Source Type: research
SUMMARY Sodium-glucose cotransporter-2 inhibitors (SGLT2i) are drugs that act by maintaining glycosuria. Recent studies have shown promising effects of these in the treatment of type 2 diabetes mellitus (DM2). However, there may be an increased risk of developing urinary tract infections (UTIs) in patients treated with these. Our study aims to analyze the association between the risk of UTI in patients treated with SGLT2i. A systematic review of the literature was carried out by randomized clinical trials, totalizing at the end of the selection 23 articles that were statistically evaluated. The incidence of UTI was general...
Source: Revista da Associacao Medica Brasileira - Category: General Medicine Source Type: research
Because weight control is a cornerstone of diabetes management, it is important to understand the relationship of weight change to risk of cardiovascular disease (CVD) among patients with type 2 diabetes melli...
Source: Cardiovascular Diabetology - Category: Cardiology Authors: Tags: Original investigation Source Type: research
Carbohydrate quality is key for a healthy and sustainable diet, Published online: 19 March 2019; doi:10.1038/s41574-019-0190-xThe quality of carbohydrate-rich foods rather than quantity has the strongest effect on major health outcomes. Systematic reviews and meta-analyses of prospective studies report lower mortality and reduced incidence of cardiovascular diseases, type 2 diabetes mellitus and colorectal cancer in people who habitually consume diets rich in fibre and whole grain.
Source: Nature Reviews Endocrinology - Category: Endocrinology Authors: Source Type: research
AbstractAimsOur study aimed to look at the prevalence and patterns of cardiac autonomic neuropathy related dysfunction in male patients of type 2 diabetes mellitus with chronic Charcot ’s foot.MethodsA total of 74 male patients with type 2 diabetes mellitus were included in this study. Three groups of patients were selected: Group 1 included patients with chronic Charcot ’s foot (n = 24), group 2 included patients with diabetic peripheral neuropathy without chronic Charcot’s foot (n = 22) and group 3 included patients without peripheral neuropathy or chronic Charcot’s foot (n...
Source: International Journal of Diabetes in Developing Countries - Category: Endocrinology Source Type: research
ConclusionGut microbiota composition was explored to be related to the occurrence of biopsy-proven DN from DM. DM could be distinguished from HC by detectingg_Prevotella_9 level in feces, while DN was different from DM by the variables ofg_Escherichia-Shigella andg_Prevotella_9, which potentially contributed to the physiopathological diagnosis of DN from DM.
Source: Acta Diabetologica - Category: Endocrinology Source Type: research
Diabetes is an independent risk factor for stroke disease. Fasting during Ramadan, Muslims must abstain from eating, drinking, taking oral medications, and smoking from the exact time of dawn until time of sunset; in this study we investigated if there is impact of Ramadan Fasting on incidence of Cerebrovascular stroke among Patients with Type 2 Diabetes Mellitus. This cross sectional study was conducted in medical ICU of Zagazig University Hospitals, in months of Sha ’ban, Ramadan and Shawwal, in 1436; total numbers of 220 patients diagnosed as cerebrovascular stroke were enrolled in.
Source: Diabetes Research and Clinical Practice - Category: Endocrinology Authors: Source Type: research
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