Detecting neurodevelopomental effects of early-gestation ethanol exposure: a non-human primate model of ethanol drinking during pregnancy.

CONCLUSION: This FASD model takes advantage of the similarities between humans and rhesus macaques in gestational length relative to brain development, as well as similarities in ethanol self-administration and metabolism. The daily 1.5 g/kg dose of ethanol through the first trimester does not influence pregnancy success rates. However, pregnancy influences drinking behavior during the second month of pregnancy. Future publications using this model will describe the effect of early-gestational ethanol exposure on anatomical and functional brain development at subsequent gestational ages. This article is protected by copyright. All rights reserved. PMID: 30549282 [PubMed - as supplied by publisher]
Source: Alcoholism, Clinical and Experimental Research - Category: Addiction Authors: Tags: Alcohol Clin Exp Res Source Type: research