Neurofibromatosis type 1

ConclusionsPatients with NF1 are at risk of eventual development of malignancy. For this reason, patients with NF1 need to be evaluated periodically by multiple specialists, using advanced imaging modalities, and it is important for dental professionals to recognize this disorder and be proactive in its interdisciplinary management.
Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology - Category: ENT & OMF Source Type: research

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Publication date: Available online 13 December 2019Source: Progress in Neuro-Psychopharmacology and Biological PsychiatryAuthor(s): Rebecca McMillan, Rachael Sumner, Anna Forsyth, Doug Campbell, Gemma Malpas, Elizabeth Maxwell, Carolyn Deng, John Hay, Rhys Ponton, Frederick Sundram, Suresh MuthukumaraswamyAbstractA single subanaesthetic dose of ketamine rapidly alleviates the symptoms of major depressive disorder (MDD). However, few studies have investigated the acute effects of ketamine on the BOLD pharmacological magnetic resonance imaging (phMRI) response and EEG spectra. In a randomised, double-blind, active placebo-co...
Source: Progress in Neuro Psychopharmacology and Biological Psychiatry - Category: Psychiatry Source Type: research
es DU Abstract Human t-cell lymphotropic virus type 1 (HTLV-1)-associated myelopathy (HAM) is a progressive neurological disease whose diagnosis is defined by clinical manifestations and seropositivity for HTLV-1 infection. Cognitive impairment (CI) is considered to occur after spinal impairment. A 51-year-old HTLV-1-infected man classified as an asymptomatic carrier presented difficulties in listening comprehension and executive memory. He was assessed for central auditory processing (CAP), cognition (event-related auditory evoked potential [P300]), and otoneurological functions (galvanic vestibular-evoked myogen...
Source: The American Journal of Tropical Medicine and Hygiene - Category: Tropical Medicine Authors: Tags: Am J Trop Med Hyg Source Type: research
Publication date: Available online 14 December 2019Source: NeuroImageAuthor(s): Daan Christiaens, Jelle Veraart, Lucilio Cordero-Grande, Anthony N. Price, Jana Hutter, Joseph V. Hajnal, J-Donald TournierAbstractProbing microstructure with diffusion magnetic resonance imaging (dMRI) on a scale orders of magnitude below the imaging resolution relies on biophysical modelling of the signal response in the tissue. The vast majority of these biophysical models of diffusion in white matter assume that the measured dMRI signal is the sum of the signals emanating from each of the constituent compartments, each of which exhibits a d...
Source: NeuroImage - Category: Neuroscience Source Type: research
Publication date: Available online 13 December 2019Source: NeuroImageAuthor(s): Erez Simony, Catie ChangAbstractNaturalistic stimuli offer promising avenues for investigating brain function across the rich, realistic spectrum of human experiences. Functional magnetic resonance imaging (fMRI) studies of brain activity during naturalistic paradigms have provided new information about dynamic neural processing in ecologically valid contexts. Yet, the complex, uncontrolled nature of such stimuli -- and the resulting mixture of neuronal and physiological responses embedded within the fMRI signals -- present challenges with resp...
Source: NeuroImage - Category: Neuroscience Source Type: research
In this report we conclude normal inflammatory markers cannot be used as exclusion criteria for the disease. We also review the body of literature to summarise the key features of the condition to assist clinicians in its diagnosis.
Source: Journal of Clinical Neuroscience - Category: Neuroscience Source Type: research
Publication date: Available online 13 December 2019Source: Journal of Clinical NeuroscienceAuthor(s): Shoko Hara, Yoji Tanaka, Yasuhiro Ueda, Daisu Abe, Shihori Hayashi, Motoki Inaji, Taketoshi Maehara, Kenji Ishii, Tadashi NariaiAbstractIt is unclear whether the visual assessment of noninvasive arterial spin labeling magnetic resonance imaging (ASL) can identify instances of hemodynamic compromise including an elevated oxygen extraction fraction (OEF) measured by 15O-gas positron emission tomography (PET). Here we evaluated the relationship between a four-point visual assessment system referred to as 'ASL scores' using AS...
Source: Journal of Clinical Neuroscience - Category: Neuroscience Source Type: research
CONCLUSIONS: Absolok® clips are a valid alternative to Hem-o-Lok® clips to secure blood vessels at the level of tumor bed and to perform a sliding-clip renorrhaphy in patients who underwent open or robot-assisted partial nephrectomy. PMID: 31833724 [PubMed - as supplied by publisher]
Source: Minerva Urologica e Nefrologica - Category: Urology & Nephrology Tags: Minerva Urol Nefrol Source Type: research
Authors: Mershon JP, Tuong MN, Schenkman NS Abstract INTRODUCTION: Thermal ablation is increasingly utilized as a management strategy for small renal masses (
Source: Minerva Urologica e Nefrologica - Category: Urology & Nephrology Tags: Minerva Urol Nefrol Source Type: research
CONCLUSIONS: Three USP steroids resulted significantly altered in our PCa population. These preliminary results, combined with the simplicity and low-cost of the analysis, open to further investigation of the potential role of this restricted USP in PCa diagnosis. PMID: 31833333 [PubMed - as supplied by publisher]
Source: Minerva Urologica e Nefrologica - Category: Urology & Nephrology Tags: Minerva Urol Nefrol Source Type: research
Authors: Bozzini G, Seveso M, Romero Otero J, Osmolorskij B, Garcia Cruz E, Margreiter M, Verze P, Besana U, Buizza C Abstract BACKGROUND: Frozen section analysis (FSA) is frequently performed during partial nephrectomy (PN). We investigate the utility of intraoperative FSA by evaluating its impact on final surgical margin (SM) status. METHODS: Between January 1995 and December 2005 we prospectively analysed a series of patients who were treated with open PN for Renal Cell Carcinoma. During PN each patient underwent a FSA on renal parenchyma distal margin . If FSA was positive for infiltration a deeper excision...
Source: Minerva Urologica e Nefrologica - Category: Urology & Nephrology Tags: Minerva Urol Nefrol Source Type: research
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