TBX1 functions as a tumor suppressor in thyroid cancer through inhibiting the activities of PI3K/AKT and MAPK/ERK pathways.

CONCLUSIONS: Our data show that TBX1 is frequently inactivated by promoter methylation, and functions as a potential tumor suppressor in thyroid cancer through inhibiting the activities of PI3K/AKT and MAPK/ERK signaling pathways. PMID: 30543152 [PubMed - as supplied by publisher]
Source: Thyroid : official journal of the American Thyroid Association - Category: Endocrinology Tags: Thyroid Source Type: research