Do All Patients With Polycythemia Vera or Essential Thrombocythemia Need Cytoreduction?

This article reviews existing data on cytoreduction, evaluating hydroxyurea, interferons, and ruxolitinib in ET and PV. This review evaluates whether evidence supports a more liberal strategy of cytoreduction for all patients with ET and PV. PMID: 30545998 [PubMed - in process]
Source: Journal of the National Comprehensive Cancer Network : JNCCN - Category: Cancer & Oncology Tags: J Natl Compr Canc Netw Source Type: research

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Resumen Paciente de 78 a ños consulta por sangrado sin resolución, a nivel del reborde alveolar maxilar izquierdo. Con antecedentes de metástasis óseas tratadas con ácido zoledrónico endovenoso discontinuado por alta médica y tratamiento quirúrgico previo de osteonecrosis maxilar en sitio afectado. Se observó disru pción de continuidad con inflamación a nivel del reborde óseo, con salida de contenido hemático, purulento y necrótico. Radiográficamente se observó radiolucidez difusa y osteolítica del á...
Source: Odontoestomatologia - Category: Dentistry Source Type: research
Men with localized prostate cancer who opt for surgery instead of surveillance are more than twice as likely to regret their decision.Medscape Medical News
Source: Medscape Hematology-Oncology Headlines - Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news
RefleXion Medical's biology-guided radiotherapy has received a breakthroug...Read more on AuntMinnie.comRelated Reading: RefleXion to showcase tech, abstracts at ASTRO 2021 Lantheus, RefleXion to collaborate on prostate cancer treatment RefleXion to install X1 at cancer center in Texas RefleXion raises another $40M, mulls Asia strategy RefleXion, Telix partner on high-risk cancer treatments
Source: Headlines - Category: Radiology Source Type: news
The development, progression, and therapy response of cancer is determined by the evolution of intratumor heterogeneity. How extracellular matrix (ECM) remodeling regulates the phenotypic diversity of tumor and stromal cells and which consequences these changes have on malignancy, however, remains poorly understood. Increasing knowledge of these connections is critical as aberrant ECM remodeling often precedes tumor development (e.g. during obesity), regulates many different hallmarks of cancer including proliferation, metabolism, and angiogenesis, and can be used to diagnose and treat cancer more effectively. Studying the...
Source: Videocast - All Events - Category: General Medicine Tags: Upcoming Events Source Type: video
Diffusion-weighted imaging has made strides in research on its way to bein...Read more on AuntMinnie.comRelated Reading: Could nonscanning factors affect abbreviated MRI workflow? Breast MRI shows effects of IUDs on body Women give thumbs-up to abbreviated breast MRI Breast MRI during workup of DCIS can spur anxiety in women AI of MRI shows success in ruling out cancer in dense breasts
Source: Headlines - Category: Radiology Source Type: news
CANCER is among the leading causes of death worldwide, but if signs are caught early prognosis is often improved.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Spesana has partnered with Biodesix Inc., a Colorado-based diagnostics solutions business that provides molecular diagnostics tests, with a focus on lung cancer.
Source: Health Care:Biotechnology headlines - Category: Biotechnology Authors: Source Type: news
Lack of attention to sexual health threatens quality of life for cancer survivors.'Oncologists need to recognize that this is an issue,'says one.Medscape Medical News
Source: Medscape Hematology-Oncology Headlines - Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news
Background Gingivitis and periodontitis are prevalent inflammatory diseases of the periodontal tissues. Current treatments are often ineffective or do not prevent disease recurrence. Uncontrolled complement activation and the resulting chronic gingival inflammation are hallmarks of periodontal diseases. We determined the efficacy and safety of a complement 3–targeted therapeutic, AMY-101, which was locally administered to adult patients with periodontal inflammation.Methods Thirty-two patients with gingival inflammation were enrolled in a randomized, placebo-controlled, double-blind, split-mouth phase IIa trial that ...
Source: Journal of Clinical Investigation - Category: Biomedical Science Authors: Source Type: research
Conclusions The major common COVID-19 genetic risk factor is associated with increased risks of morbidity and mortality, which are more pronounced among individuals 60 years or younger. The effect was similar in magnitude and more common than most established clinical risk factors, suggesting potential implications for future clinical risk management.
Source: Journal of Clinical Investigation - Category: Biomedical Science Authors: Source Type: research
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