The Streptococcos suis sortases SrtB and SrtF are essential for disease in pigs.

In this study, markerless in-frame deletion mutants of the housekeeping sortase srtA and the two pilus-associated sortases, srtB and srtF, were generated and their importance in S. suis infections was investigated. We found that all three of these sortases are essential to disease in pigs, concluding that their cognate-sorted proteins may also be useful in protecting pigs against infection. PMID: 30543506 [PubMed - as supplied by publisher]
Source: Microbiology - Category: Microbiology Authors: Tags: Microbiology Source Type: research