Alternative transcript imbalance underlying breast cancer susceptibility in a family carrying PALB2 c.3201+5G & gt;T

ConclusionsOur results support a pathogenic classification forPALB2 c.3201+5G>T, highlighting the impact of variants causing an imbalanced expression of natural RNA isoforms in cancer susceptibility.
Source: Breast Cancer Research and Treatment - Category: Cancer & Oncology Source Type: research