Insecticide Resistance Associated with kdr Mutations in Aedes albopictus: An Update on Worldwide Evidences.

Insecticide Resistance Associated with kdr Mutations in Aedes albopictus: An Update on Worldwide Evidences. Biomed Res Int. 2018;2018:3098575 Authors: Auteri M, La Russa F, Blanda V, Torina A Abstract Insecticide resistance is an increasing problem worldwide that limits the efficacy of control methods against several pests of health interest. Among them, Aedes albopictus mosquitoes are efficient vectors of relevant pathogens causing animal and human diseases worldwide, including yellow fever, chikungunya, dengue, and Zika. Different mechanisms are associated in conferring resistance to chemical insecticides. One of the most widespread and analysed mechanisms is the knockdown resistance (kdr) causing resistance to DDT and pyrethroids. The mechanism is associated with mutations in the voltage sensitive sodium channel, which is involved in beginning and propagation of action potentials in nervous cells. The mechanism was originally discovered in the housefly and then it was found in a large number of arthropods. In 2011, a kdr associated mutation was evidenced for the first time in A. albopictus and afterward several evidences were reported in the different areas of the world, including China, USA, Brazil, India, and Mediterranean Countries. This review aims to update and summarize current evidences on kdr in A. albopictus, in order to stimulate further researches to analyse in depth A. albopictus resistance status across the world, esp...
Source: Biomed Res - Category: Research Authors: Tags: Biomed Res Int Source Type: research